Cctv newsAccording to Beijing Municipal Bureau of Statistics and Beijing Investigation Corps of National Bureau of Statistics, 2023 is the first year to fully implement the spirit of the 20th Party Congress, and the year of economic recovery and development after three years of COVID-19 epidemic prevention and control. Faced with various internal and external risks and challenges, under the strong leadership of the CPC Central Committee with the Supreme Leader as the core, the city has made great efforts to stabilize the economy, promote development and improve people’s livelihood. The overall economic recovery has improved, the social and people’s livelihood security has been strong, and the high-quality development of the capital has been solidly promoted. The latest statistical bulletin of Beijing’s national economic and social development in 2023 issued by Beijing Municipal Bureau of Statistics and Beijing Investigation Corps of National Bureau of Statistics records the new progress and achievements of various undertakings in the capital in the past year with rich statistical data.

　　First, the macro-policies have exerted remarkable effects, and the economy has continued to pick up.

　　Resolutely implement the decision-making arrangements of the CPC Central Committee and the State Council and the work requirements of the municipal party committee and municipal government, adhere to the general tone of striving for progress while maintaining stability, focus on expanding domestic demand, optimizing the structure, strengthening innovation, and protecting people’s livelihood. Macro-control policies continue to exert significant effects, and the overall economy continues to pick up. The annual GDP was 4,376.07 billion yuan, an increase of 5.2% compared with the previous year at comparable prices. According to the resident population, the per capita GDP of the city reached 200,000 yuan, keeping the best level among provincial regions in China. The employment and price situation is generally stable. The annual consumer price rose by 0.4% over the previous year, and the average unemployment rate in urban areas was 4.4%, which was 0.3 percentage points lower than that in the previous year, and it was within the annual control target.

　　Economic development shows strong resilience and potential. The main areas have risen steadily. The added value of the service industry increased by 6.1% over the previous year, which is higher than the growth level of regional GDP. It is the main driving force for economic recovery, driven by the continuous support of the information service industry and the financial industry. Industrial production stopped falling and rebounded, and the added value of industrial enterprises above designated size increased by 0.4%. The equipment, electric power and automobile industries made outstanding contributions. The investment in fixed assets (excluding farmers) increased by 4.9% in the whole year, and the investment in construction and installation projects reflecting the physical workload and the investment in equipment purchase reflecting the expansion of production capacity of enterprises accounted for 56.2%, an increase of 0.5 percentage points over the previous year. Consumption continued to recover, and the total market consumption increased by 10.2% over the previous year. Among them, service consumption increased by 14.6% driven by transportation, culture, sports and entertainment, and the total retail sales of social consumer goods increased by 4.8%. The benefits of enterprises have gradually improved, and the vitality of development has been enhanced. Industrial and service enterprises above designated size achieved operating income of 2.8 trillion yuan and 17.3 trillion yuan respectively, up by 3.6% and 2.0% respectively over the previous year. In 2001, 297,000 new enterprises were established, an increase of 20.3%. The output value of "specialized and innovative" industrial enterprises above designated size and the income of service enterprises increased by 5.2% and 6.1% respectively, and the growth rate was 2.6 and 4.1 percentage points higher than the average level of industries and service industries above designated size respectively.

　　Second, promote the synergy of the "five sons" and make new breakthroughs in high-quality development

　　Adhere to the "five sons" linkage service and integrate into the new development pattern, and the quality of economic development in the capital has been continuously improved.

　　Accelerate the construction of an international science and technology innovation center. The ability to innovate has been continuously enhanced. The investment intensity of research and experimental development (R&D) in the whole society (the ratio of research and experimental development funds to regional GDP) has remained above 6% continuously since 2019, ranking first in all provinces (autonomous regions and municipalities) in China. From January to November 2023, the research and development expenses of large and medium-sized key enterprises above designated size totaled 350.11 billion yuan, up 4.6% year-on-year, of which the research and development expenses of industrial, scientific and technological service enterprises achieved double-digit growth. At the end of the year, there were 574,000 valid invention patents in the city, up by 20.2%, and the number of high-value invention patents per 10,000 people was 136.95, up by 24.97. Innovation empowers high-end industry development. The added value of high-tech industries in the whole year was 1,187.54 billion yuan, an increase of 7.1% over the previous year at current prices, accounting for 27.1% of the regional GDP, an increase of 0.4 percentage points over the previous year.

　　Promote the construction of a global digital economy benchmark city. The added value of the digital economy was 1,876.67 billion yuan, accounting for 42.9% of the city’s regional GDP, up 1.3 percentage points over the previous year. Build a smart city, implement the action plan of "the capital of optical network, the city of ten thousand megabytes", and build a total of 107 thousand 5G base stations, ranking first in all provinces (autonomous regions and municipalities) per 10 thousand people; The cumulative number of gigabit users reached 2.287 million, an increase of 943,000 over the previous year; The application terminals of "Jingtong", "Beijing Office" and "Jingzhi" in three smart cities have been rapidly upgraded and expanded, and the application of digital technology in key areas such as travel and medical care has been deepened.

　　Steadily promote the cultivation and construction of international consumption center cities. Consumer supply is more abundant. In the whole year, 61,000 new wholesale and retail, accommodation and catering enterprises were established, an increase of 15.6% over the previous year; Newly introduced 946 first stores, an increase of 16.5%; By the end of the year, there were 1,058 departure tax refund shops, an increase of 41. New consumption patterns such as e-commerce live broadcast and instant retail have developed rapidly. The online retail sales of convenience stores, supermarkets and warehouse member stores accounted for 28.6% of the retail sales of the three formats, an increase of 2.5 percentage points over the previous year. Scenarios and experiential consumption, such as performances and competitions, were active, with 49,524 performances held in 339 performance venues throughout the year, an increase of 1.4 times over the previous year; The performance income totaled 2.3 billion yuan, an increase of 2.7 times.

　　Promote high-level opening up with the construction of "two districts" Beijing’s first national-level cross-border trade facilitation standardization pilot project will be built, and a new international trade service platform of "Jingmaoxing" will be built to support the high-quality development of the comprehensive insurance zone. In the whole year, the total import and export value of Beijing was 3.6 trillion yuan, up by 0.3% over the previous year. The total import and export value of China (Beijing) Pilot Free Trade Zone (hereinafter referred to as Pilot Free Trade Zone) was 462.43 billion yuan, up by 2.7%. Among the key industries in which the service industry is expanding and opening up, 1,321 foreign-funded enterprises have been established in scientific research and technical services, leasing and business services, culture, sports and entertainment, accounting for more than 70% of the newly-established foreign-funded enterprises in the city, and 258 foreign-funded enterprises have been established in the Pilot Free Trade Zone, accounting for 14.9%.

　　The coordinated development of Beijing-Tianjin-Hebei has deepened and deepened. In the whole year, 112 general manufacturing enterprises were relieved and upgraded, and 23.15 million square meters of illegal construction was controlled. The construction of the city sub-center maintained the investment intensity of 100 billion yuan, and the second batch of municipal authorities completed the relocation, with more than 20,000 registered enterprises in the Canal Business District. Collaborative innovation and industrial cooperation are closer. Beijing, Tianjin and Hebei jointly built the Beijing-Tianjin-Hebei National Technology Innovation Center and compiled six key industrial chain maps. The turnover of technology contracts from Beijing to Tianjin and Hebei increased by 1.1 times over the previous year. Xiong’an new area Zhongguancun Science Park was unveiled for operation, and more than 30 innovative enterprises and 11 Zhongguancun integrated service organizations settled in.

　　Third, pay attention to the people’s "urgent difficulties and worries" and continue to promote the improvement of people’s livelihood

　　We will thoroughly implement the people-centered development idea, focus on the people’s urgent difficulties and worries, stabilize the "rice bag" and "vegetable basket", strive to increase the income of urban and rural residents, improve the level of public services, and enhance the people’s sense of happiness and gain.

　　Stable production and strong supply of agricultural products. Overcoming the adverse effects of natural disasters, the annual grain planting area was stable at more than 1 million mu, and the total grain output was 478,000 tons, an increase of 5.3% over the previous year, achieving "four consecutive increases" since 2020. The planting area of vegetables and edible fungi was 795,000 mu, and the output was 2.075 million tons, an increase of 4.3%.

　　Residents’ income has increased steadily. The per capita disposable income of the city’s residents was 81,752 yuan, a real increase of 5.2% after deducting the price factor, which was in step with the economic growth. Among them, the per capita disposable income of rural residents increased by 7.5%, 2 percentage points higher than that of urban residents. The per capita disposable income ratio of urban and rural residents was 2.37, which was 0.05 lower than that of the previous year.

　　The policy strengthens the guarantee. Fiscal expenditure is tilted towards the people’s livelihood. Among the general public budget expenditures in the city, the proportion of education, social security, employment and health expenditure remains at around 40%. Housing security has been continuously strengthened. In the whole year, 82,000 sets (rooms) of affordable rental housing were built and 93,000 sets (rooms) of various types of affordable housing were completed. There are 355 newly started communities and 183 newly completed communities in the transformation of old communities in the city. The coverage of social security continued to expand. At the end of the year, the number of employees participating in basic old-age insurance, unemployment insurance and industrial injury insurance increased by 368,000, 270,000 and 269,000 respectively.

　　The level of public services continued to improve. By the end of the year, there were 12,518 medical and health institutions with 139,000 beds and 343,000 health technicians. There are 1991 kindergartens, and the coverage rate of inclusive kindergartens reaches 93%. A total of 1,772 old-age meals have been built, covering nearly 5,000 urban and rural communities and more than 2.8 million people. There are 20 public libraries and 226 museums in the city, of which 107 are open for free, 18 are cultural centers and 339 are cultural stations. Throughout the year, 43 demonstration streets for national fitness and towns with sports characteristics were established.

　　Fourth, practice the concept of people’s city and improve the quality of the city.

　　We will fully implement the green development strategy, promote the transformation of urban management to urban governance and service with embroidery skills, focus on improving the ecological environment, and continuously improve the quality of urban life.

　　Strengthen urban operation guarantee. The annual sales volume of tap water was 1.33 billion cubic meters, an increase of 7.8% over the previous year. The electricity consumption in Beijing was 135.78 billion kWh, an increase of 6.0%. The total supply of natural gas was 20.61 billion cubic meters, an increase of 3.5%. The heating area of over 100,000 square meters was 730 million square meters, an increase of 2.4%. The annual sewage treatment rate was 97.3%, an increase of 0.3 percentage points. The city cleared and disposed of 7,588,500 tons of domestic garbage, with an average of 20,800 tons per day; There are 34 centralized treatment facilities for domestic waste, with an actual treatment capacity of 28,426 tons/day.

　　Improve the green travel service. At the end of the year, there were 1,285 bus lines, 29,738.5 kilometers of lines and 23,385 vehicles. There are 27 rail transit lines, with a length of 836 kilometers, an increase of 38.7 kilometers over the previous year, and 7512 vehicles, an increase of 238 vehicles. At the end of the year, there were 916,000 vehicles in bike-sharing, an increase of 35,000 vehicles over the end of last year.

　　Build a beautiful and livable environment. We will continue to fight the "blue sky defense war", and the four major pollutants in the city’s atmospheric environment will continue to reach the national air quality secondary standard. New steps have been taken in the construction of garden cities, promoting the construction of leisure parks, urban forests, pocket parks, small and micro green areas, etc. The annual urban green coverage rate reached 49.8%, and the per capita park green area reached 16.9 square meters.

　　In 2023, under the strong leadership of the CPC Central Committee and through the hard work of the whole city, new progress was made in various undertakings in the capital. The year 2024 marks the 75th anniversary of the founding of New China, a crucial year for achieving the objectives and tasks of the 14th Five-Year Plan, and the 10th anniversary of the implementation of the coordinated development strategy of Beijing-Tianjin-Hebei. We should adhere to the guidance of the Supreme Leader’s Socialism with Chinese characteristics Thought in the new era, fully implement the decision-making arrangements of the CPC Central Committee, thoroughly implement the spirit of the important speech of the Supreme Leader General Secretary to Beijing, persist in striving for progress while maintaining stability, making progress before breaking, and concentrate on strengthening functions, stabilizing growth, benefiting people’s livelihood, ensuring stability and ensuring stability.

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　　In 2023, Beijing achieved a regional GDP of 4,376.07 billion yuan, an increase of 5.2% over the previous year.

　　A COVID-19 allowed time to freeze, and at the same time, some entrepreneurs who had pressed the fast forward button revealed their true colors, which made people think. The second-hand recycling platform loves recycling, perhaps one of them. Author: Wang Qiji ━ ━ ━ ━ ━ "When the tide ebbs, you know who is swimming naked". -Buffett’s COVID-19 made time freeze, and at the same time, it also made some entrepreneurs who had pressed the fast forward button show their true colors, which made people think. The second-hand recycling platform loves recycling, perhaps one of them. The Spring Festival in 2020 seems to be a watershed, which has changed many people and may also change the fate of many enterprises in the future. On January 9, 2020, Hurun Research Institute released "2019 Hurun China Top 500 Private Enterprises", ranking 468 th in love recycling; However, before the Spring Festival, there were rumors that Zheng Fujiang, a recycling partner, left his job and his cash flow was tight. Employees who leave their jobs with love recycling said on social platforms that Zheng Yujiang chose to leave his job before the Spring Festival and love recycling. After the Spring Festival, some people in the investment circle also broke the news that they had signs of leaving. At the same time, love recycling was also revealed by employees: the company’s five insurances and one gold in January 2020 have not been paid yet. What is the real situation? GPLP rhinoceros finance conducted a verification.

　　Zheng Yujiang, president of Chuanai Recycling, left?

　　

　　Has Zheng Fujiang retired from his job? GPLP Rhino Finance hereby calls itself for verification, but it is denied by the other party, and no further explanation is given. So what’s going on inside employees and in the investment circle? Judging from the information collected so far, everything is not groundless. On February 11th, 2020, on the platform of Love Recycling Enterprise-"Love Recycling Fresh Release" WeChat, an article called "Let’s Work Hard"
The article "Walking Against the Wind-Opening Meeting and Headlines of Love Recycling" shows that Chen Xuefeng, founder and ＆CEO of Love Recycling, and Wang Yongliang, partner and co-president of Love Recycling, all delivered relevant speeches, but only Zheng Fujiang was missing.

　　On January 22nd, GPLP Rhino Finance didn’t find Zheng Fujiang to speak in the annual meeting of Love Recycling.

　　There are indications that, as an important member of the recycling-loving senior management, even though Zheng Fujiang denied that he didn’t leave his job and love recycling, something may have happened inside this startup. According to public information, in the first half of 2016, Zheng Fujiang, a former CMO of Huawei China District, joined Airecycling. In the past four years, he has made great contributions to the expansion of Airecycling and has been loved by many internal employees. "Its internal prestige is very high," disclosed by people in the investment circle who have been in contact with recycling. It is reported that after joining Love Recycling, Zheng Fujiang once built an offline cooperation channel network of Love Recycling. According to public information, during Zheng Yujiang’s four years of love recycling, love recycling has 300 direct stores in the core business districts of first-tier cities, and besides direct stores, love recycling also has seven operation centers including Hong Kong, Shanghai, Changzhou, Chengdu and Wuhan, with a total operating area of over 40,000 square meters. According to the data released by Love Recycling, the company actually has more than 600 stores and thousands of employees in the country, with more than 1,000 employees only at the peak of the staff. It can be said that it is Zheng Fujiang’s joining that makes love recycling have the offline leg. Is it leaving now, or is it gradually fading out? Or just the job responsibilities have been adjusted? Regarding the follow-up developments, GPLP Rhino Finance will continue to pay attention.

　　Love recycling, tight cash flow?

　　An unexpected event after the Spring Festival in 2020 really surprised everyone. Similarly, this also includes love recycling. In this regard, in the internal enterprise platform of Love Recycling, "Love Recycling Fresh Release" is about "Gathering Hard Work"
In the WeChat of Walking Against the Wind, Chen Xuefeng, the founder and ＆CEO of Airecycling, said that "to live is to be strong", and the goal of Airecycling Q2 is to approach the break-even point of the group and achieve full profit in the second half of the year.

　　At the same time, Chen Xuefeng also said, "In the face of cruel figures and reality, we must make worse plans." "We carefully predict that at least in the next 3-6 months, all walks of life will face a crisis of life and death, which is far more severe than Sars in 2003. Then, can love recycling survive this life-and-death crisis and cruel figures and reality, as executives say, "live"? This will test the cash flow of love recycling. However, regarding the cash flow of recycling, it seems that it is not optimistic from the current information of all parties.

　　According to its employees who broke the news on social platforms, as of February 19, 2020, Love Recycling has not issued its five insurances and one gold to employees in January. Is this true? At present, its official has not responded. However, before it gives the goal of achieving breakeven in Q2, GPLP Rhino Finance can judge that the current love recycling has not achieved breakeven and is obviously at a loss, and the current operation should mainly rely on financing. In this regard, in "Let’s work hard"
In the article "Walking Against the Wind", Chen Xuefeng, the founder & ＆CEO of Love Recycling, also publicly stated, "Last Friday, we had clearly won the strong support of JD.COM for the first time. Therefore, there is a big tree behind JD.COM. What are we panicking about?" However, can investment institutions solve the problems of enterprises and various cash flows? I’m afraid this is a bit difficult. On June 3, 2019, Airecycling announced that JD.COM Group General Airecycling had a new round of financing and strategic integration transactions of more than 500 million US dollars, and the two sides had reached a final agreement. According to the official website announcement of the Securities and Exchange Commission of the United States, JD.COM Group actually invested nearly $20 million in cash for the investment that loves recycling. Now, according to June 2019, seven months have passed. So, how much money is there in the unfunded love recycling account? Can this cash support Airecycling more than 600 offline stores and thousands of employees to survive Q1 or Q2 in early 2020? This is a problem. If the cost of employees can be controlled by layoffs that have been reported before, in front of more than 600 offline stores, it is obviously difficult to control cash flow. Just like Xinchao Media, which started to lay off employees in 2020, even though there is still 1 billion yuan in cash in its account, at the staff meeting on the first day of work, Xinchao Media announced that it would lay off 500 employees, accounting for 10% of the total number of employees, and the senior management collectively reduced their salary by 20%. So, how will love recycling spend this cash flow problem?Will love recycling save itself by cutting off the closing of offline stores and reducing wages and layoffs? I’m afraid only love recycling is clear inside. However, as of press time, the inquiry request of GPLP Rhino Finance has not been answered. In addition to cash, this sudden epidemic has actually brought thinking to startups. Does the blind expansion of offline stores conform to the strength of the enterprise itself? Put the hope of survival on the investor’s thigh, and how much continuous blood transfusion can you get when the capital market is getting colder? Put the hope of living in the hands of others, how long can you last without online traffic that can make your own decisions?

　　"God helps those who help themselves"

　　Whether love recycling can survive hundreds of offline stores safely, and the dilemma of "stopping" and lack of traffic caused by the serious lack of passenger flow at present is obviously a very big test for it in 2020.

　　The reason is not unrelated to its rapid expansion for many years, so both cash flow and its management, including its operation mode, are worthy of reflection.

　　Perhaps, love recycling has found problems and started to adjust, so the news of personnel changes came out.

　　In addition, this emergency has also taught more enterprises the most important lesson, that is, don’t be blindly optimistic, don’t be overly obsessed with the satisfaction brought about by expansion, and must have a clear understanding of their own capabilities; At the same time, it is very important to pay attention to cash flow management.

　　Regarding the importance of cash flow, Allen Zhu, a partner of Jinshajiang Venture Capital, said on February 2, 2020, "When I was still starting a business in SARS in 2003, the management only took the basic living expenses that year, and the salary was reissued after the balance at the end of the year. This year is more severe than SARS, which is a matter of life and death for many start-ups. We must strictly control the cost and keep the cash for at least 6 months, preferably 12 months, assuming that there is no income. According to this, we can calculate the cost. Live on your knees, and it will be spring in the past! "

　　Allen Zhu also said, "After the epidemic, it will take two or three months for the enterprise to recover its operational data, and it will take another two or three months for it to raise funds after data recovery, so it may take four to six months from the end of the epidemic to getting the money. Entrepreneurs must prepare for the worst, and their income will be less in the first half of the year. They must make the most conservative plan and control cash. "

　　However, it is difficult to change the matter of controlling cash in a short time. Especially when sudden events bring difficulties to a large number of offline-oriented enterprises, how much time will be left to the decision makers of enterprises? After all, the rent of 600 stores and the salary of thousands of employees are already extremely high.

This article first appeared on WeChat WeChat official account: GPLP. The content of the article belongs to the author’s personal opinion and does not represent Hexun.com’s position. Investors should operate accordingly, at their own risk.

　 　 　 　As a youth-oriented industry, the actress at this age (24 years old) of Nagata has already needed to consider pulling out. In the past, these retired AV actresses either stayed at home and taught their children, or completely lost their news, thus achieving a real retirement.

　 　 　 　It’s ok to continue in the AV business, and some people choose to go behind the scenes and become makeup artists. After all, as an old-timer, my skills in all aspects are always better than those of my younger generation.

　 　 　 　At the beginning, there was a female group named "Ebisu Muscats" that attracted attention. All the members of the group were retired AV actresses, nightclub publicists and so on. After packaging, they made various variety shows and performances together.

　 　 　 　Up to now, this women’s group has changed many groups of members. Even if the new members don’t look so familiar, if you search its information, you will surely see many "old acquaintances" among the past members.

　 　 　 　Of course, when it comes to the transformation of actresses, Kirara Asuka is bound to be an unavoidable topic. After retiring early, she not only invested in a beauty shop, but also did a great job in designing swimwear and underwear. Even in August last year, Teacher Tomorrow Flower’s hotel was opened.

　 　 　 　Perhaps no one could have thought that this former top actress had such a strong talent in business.

　 　 　 　However, the above paths are either not easy or not so comfortable. Some people are as prosperous as Kirara Asuka, but some people also lose their wives’ money when they start a business. Ueharaai, another well-known actress, chose a business that is comfortable and can make quick money — — Speculate virtual currency.

　 　 　 　Not only do I share my experience with netizens on Twitter every day, but I also believe that it will rise with confidence, and then there is the leek behavior of "others are afraid that I am crazy, and others will clear their positions and I will add positions". As for what the virtual currency market is like recently, I think most of your friends have heard of it.

　 　 　 　Incidentally, Ueharaai, who lost all his wife, was forced to "make a comeback" earlier this year (but it seems that she only performed offline).

　 　 　 　It is under the influence of the general environment that "online celebrity", a glamorous and comfortable job with almost zero cost, may become the home of more and more female talents.

　 　 　 　It’s just like the "most popular actress" list published every year. The popularity of social platforms is also the embodiment of these teachers’ achievements in another field. The success of Kirara Asuka and Shentian’s praise of beauty undoubtedly tells the outside world that there are always two brushes to achieve top flow in one line.

　　Under the background of deepening reform in an all-round way, carrying out the innovation-driven development strategy in depth and China’s economy entering a new normal, the CPC Central Committee and the State Council attach great importance to mass entrepreneurship and innovation, and a new wave of innovation and entrepreneurship is surging in China, providing sustained impetus for China’s economic development.

　　General Secretary of the Supreme Leader pointed out at the National Science and Technology Innovation Conference held in May 2016 that science and technology are the sharp weapon of the country, and the country relies on it to be strong, enterprises rely on it to win, and people’s lives depend on it to be good. China is strong, China people’s lives are better, and we must have strong science and technology. The new era, new situation and new tasks require us to have new ideas, new designs and new strategies in scientific and technological innovation.

　　"The stable recovery of the world economy depends on innovation, and the upgrading of China’s economy depends on innovation." Premier Li Keqiang emphasized innovation at the Eighth Summer Davos Forum in 2014, and put forward "mass entrepreneurship and innovation" for the first time. Since then, he has frequently explained this keyword on various occasions. As the key work in 2016, the Government Work Report clearly puts forward that the multiplier effect of mass entrepreneurship, innovation and "internet plus" should be brought into play, and a platform of mass creation, crowdsourcing, public support and crowdfunding should be built, and a new entrepreneurial innovation mechanism should be built with the cooperation of large, medium and small enterprises, universities, scientific research institutions and makers.

　　Technological innovation and entrepreneurship are changing life, and they are also affecting China. At present, a new round of scientific and technological innovation and entrepreneurship is becoming a new engine for steady growth, promoting reform and restructuring, and a new kinetic energy for benefiting people’s livelihood, ensuring employment and promoting development.

　　The explosive growth of science and technology start-ups

　　Beijing, Zhongguancun Software Park, Didi Office Building.

　　A few days ago, our reporter came to Didi’s Beijing headquarters and felt the growth story of a company that changed the traditional mode of transportation by using the home Internet and was rated as one of the top 50 innovative enterprises in the world by MIT Science and Technology Review.

　　Back in early 2012, 29-year-old Cheng Wei was brewing a business. He believes that the Internet has fully entered the life field represented by food, clothing, housing and transportation, and "clothing, food and shelter" has a relatively mature operating model, while "travel" seems to have not. At that time, he lived in the northern suburb of Hangzhou, and he traveled every day or took the bus, subway or stood on the side of the road waving for a taxi. Combined with his own personal experience, he began to think about whether there is a way to "move" taxis to the Internet, so that people who want to take taxis know where the taxis are and drivers know where the passengers are, thus solving the problem of information asymmetry and making people’s travel more convenient.

　　With the continuous maturity of ideas, Cheng Wei and his friends Wu Rui and Li Xiang, who have always dreamed of starting a business, founded Xiaoju Technology Co., Ltd. in Beijing in June 2012, and launched mobile phone car calling software — — Didi taxi APP. In that year, they ran through more than 100 taxi companies in Beijing, and they also insisted on installing Didi taxi APP for more than 10 thousand taxi drivers at Beijing West Railway Station. People gradually find that taking a taxi with this small APP is convenient for both drivers and passengers.

　　After that, in just four years, the integration of technology, capital and talents accelerated. Today, Didi has provided comprehensive travel services for nearly 300 million users in more than 400 cities around the world, such as taxi calling, express train, hitchhiking, driving, test drive, public transportation, online car rental and enterprise-level services, and adopted cloud computing to design a new hierarchical architecture for the business, which not only can accurately match the supply and demand information between passengers and online car, but also can guide vehicles to hot spots of travel demand through automatic early warning of the platform, thus alleviating the travel pressure.

　　With the rapid development of business, Didi has received nearly 8 billion US dollars in financing, becoming the second largest online trading platform in the world after Taobao and the largest one-stop diversified travel platform in the world. At the end of September 2016, the daily order of Didi Platform reached 20 million times.

　　It is undeniable that Didi’s sudden emergence is very important because it has grasped the opportunities for the development of cutting-edge technologies such as the Internet and cloud computing.

　　Science and technology entrepreneurship has promoted technological innovation and business model innovation. Correspondingly, the innovation of technology and business model has also brought infinite possibilities to entrepreneurship. Every technological progress will give birth to new entrepreneurial fields and new entrepreneurial enterprises.

　　In August 2011, a company focused on the research, development and operation of cloud computing business centered on data management — — Qi Niuyun was formally founded in Shanghai. Only one year later, Qiniuyun became the first team in China to conduct large-scale project research and development with GO language, and realized the core service of distributed object storage system based on GO. At present, Qi Niuyun has ranked first in the domestic cloud computing industry.

　　As a leading enterprise-level cloud service provider in China, Qiniu Cloud Service has more than 500,000 corporate customers, storing more than 200 billion files and 1 billion hours of video, with a cumulative capacity of more than 100PB, attracting many corporate customers such as SF Express, Netease and Meipai. Up to now, Qiniuyun has successively set up offices in Beijing, Shenzhen, Guangzhou, Hangzhou and Chengdu, with nearly 500 employees, including more than 50% technicians.

　　According to reports, Qi Niuyun has always taken data as its core value, and continuously aggregates all kinds of data by providing an excellent cloud service platform, so that massive data can circulate. At the same time, Qi Niuyun is also committed to creating a scene PaaS to help developers shorten the distance from ideas to products. Around the rich media scene, Qi Niuyun has formed an ecological rich media cloud platform.

　　Nowadays, many enterprises like Didi and Qiniuyun are booming in China. These enterprises have transformed themselves into commercial society, accelerated the gathering of innovative elements such as talents, technology and capital, and also promoted technological innovation and enhanced social value invisibly.

　　The rapid development of these scientific and technological innovation and entrepreneurship enterprises is the epitome of the improving innovation and entrepreneurship environment in China, and it is the result of the country attaching great importance to economic development and social employment, actively encouraging innovation and entrepreneurship, and optimizing the innovation and entrepreneurship environment.

　　In recent years, China has accelerated the registration time of newly established enterprises, from the average of 26 days before the reform to 14 days, and will further shorten it to 3 days. In this context, the formation of innovative and entrepreneurial enterprise groups in China has been accelerated, and more and more people have invested in the tide of innovation and entrepreneurship, and the newly registered enterprises in various places have grown by spurt.

　　Relevant statistics show that in 2015, there were 4.439 million newly registered enterprises nationwide, an increase of 21.6% compared with 2014, and the registered capital (fund) was 29 trillion yuan, an increase of 52.2%, both of which reached new highs in the number of new registrations and the total registered capital (fund). In the first three quarters of 2016, the number of newly registered enterprises nationwide reached 4.01 million, with an average of 14,600 newly registered enterprises per day, higher than the average of 12,000 per day in 2015; The number of technology entrepreneurs of cloud computing services in China has increased from 2 million in 2015 to 2.9 million in October 2016 … … When time enters 2016, people see new data in the field of innovation and entrepreneurship and feel new leaps again and again.

　　With the gradual improvement of the business incubation environment, China’s entrepreneurial subject is moving from "minority" to "mass", and more and more post-90s youths regard entrepreneurship as their life ideal. More and more corporate executives, scientific and technological personnel and returned overseas talents are also actively involved in the entrepreneurial tide, forming the "New Fourth Army" of innovation and entrepreneurship in China.

　　The statistical data obtained from a previous survey conducted by relevant departments on the development of Beijing Zhongchuang Space also show that among the founders of the surveyed entrepreneurial enterprises, 38.4% are corporate executives, 22.2% are corporate technicians, 11.1% are returnees, 9.3% are successful entrepreneurs and 8.4% are college students & mdash; — The "New Fourth Army" has become the main force of innovation and entrepreneurship.

　　The rise of large enterprises supports the tide of innovation and entrepreneurship

　　18 years ago, Alibaba was a start-up; Eighteen years later, Alibaba has become a leading enterprise in the industry, and under the background of the country’s vigorous promotion of innovation and entrepreneurship, it has further exerted its comprehensive advantages in technology, capital, talents and market, adding fuel to the fire for innovation and entrepreneurship, which not only makes the enterprise grow continuously, but also promotes the sustainable development of China’s economy.

　　In August 2016, the General Office of the State Council issued the "Implementation Opinions on Building a Demonstration Base for Mass Entrepreneurship and Innovation", and Alibaba Group was selected as the first batch of dual-innovation demonstration bases. According to reports, Alibaba will build 100 innovation centers, support millions of small and micro innovative entrepreneurs, build a campus post to support 10,000 student entrepreneurial teams, and create a free office communication and collaboration platform for "double innovation" enterprises.

　　At present, Alibaba has deployed 22 innovation centers across the country. In 2015, it supported 864 small and medium-sized enterprises, driving nearly 10,000 entrepreneurs. In the next two years, Alibaba Innovation Center will expand its operations to a total of 100, directly driving the coverage of 30,000 entrepreneurs.

　　There is a mobile office communication collaborative multi-terminal platform under Alibaba Group — — DingTalk. Since the platform was launched two years ago, it has served more than 2.4 million enterprises or organizations free of charge, which has enabled enterprises to enter the era of efficient mobile office, not only saving costs, but also improving work efficiency. On May 31, 2015, Nail officially launched the C++strategy, and at the same time invested 1 billion yuan in the first phase to establish the Nail Ecological Development Fund.

　　At present, cloud computing has become the infrastructure of global innovation. According to Ali Research Institute, 60% of entrepreneurs in Alibaba Cloud are starting their own businesses for the first time. After the start-up enterprises choose to adopt the public cloud platform, the calculation cost is reduced by 70% and the innovation efficiency is increased by as much as 300%.

　　Today’s Alibaba Cloud serves more than half of China’s technological unicorn enterprises. Statistics show that in 2015, Alibaba Cloud served 1.8 million technology entrepreneurs; As of October 2016, it has served 2.3 million technology entrepreneurs, accounting for about 80% of the country.

　　In addition, Alibaba Group will also integrate the operations of existing Yunqi Town, Alibaba Cloud Chuangke+and Ali Baichuan Incubation Base to create a unique "double innovation" support model for Alibaba — — "1+4+N" means a Alibaba Cloud Maker+platform, four kinds of Alibaba’s unique technology empowerment, traffic empowerment, talent empowerment, ecological empowerment, e-commerce O2O, cloud computing big data, intelligent hardware, B2B enterprise service SaaS, digital entertainment and other N incubation support themes.

　　Not only Alibaba, but also a number of leading enterprises in China are engaged in the field of innovation and entrepreneurship. Haier Group is striving to transform itself from a traditional manufacturing enterprise to an entrepreneurial platform, and to become a big incubator of "providing entrepreneurial services for employees" to maximize the value of employees’ innovation and entrepreneurship. On Haier’s entrepreneurial platform, there are only three types: platform owner, small micro-owner and maker. The platform owner is the platform manager, the small micro-owner is the person in charge, and the maker is the small micro-employee. As the basic unit of an enterprise, entrepreneurial micro-enterprises are independent operating entities, enjoying decision-making power, human rights and distribution rights.

　　Haier relies on its own superior resources to provide all-factor, all-process and all-life-cycle support for entrepreneurial micro-enterprises, including design and research and development, financing, sales network, human resources, legal affairs and financial services. Haier’s entrepreneurship platform consists of six sub-platforms: Maker Lab, Maker College, Maker Factory, Maker Service, Maker Finance and Maker Base, which realize the combination of innovation and entrepreneurship, online and offline, incubation and investment, and provide low-cost, convenient and all-factor open comprehensive entrepreneurial services for entrepreneurs.

　　It is understood that at present, more than 100 small and micro-enterprises on Haier’s entrepreneurial platform have earned more than 100 million yuan, 29 small and micro-enterprises have introduced venture capital, and 14 small and micro-enterprises have been valued at more than 100 million yuan. The whole platform has provided more than 1.3 million employment opportunities for the whole society.

　　The support of leading enterprises in the industry has facilitated the development of scientific and technological innovation and entrepreneurship, accelerated the growth of entrepreneurial enterprises, and the development of entrepreneurial enterprises has injected new vitality into leading enterprises. The two promote each other and jointly form a new wave of scientific and technological innovation and entrepreneurship in China, and China’s innovation power is also constantly improving.

　　According to statistics, in the first half of 2016, the number of invention patents granted in China reached 164,000. According to the 2016 Global Innovation Index released by the World Intellectual Property Organization, Cornell University and Yingshi International Business School in Geneva, China ranks among the top 25 most innovative economies in the world for the first time. Among the 82 specific evaluation indicators covered by the index, China ranks first in the world in 10 indicators, such as the proportion of high-tech exports, knowledge-based employees, assessment of the ability of 15-year-olds (reading, mathematics and science) and company training.

　　At the same time, the contributors of these innovation indexes, scientific and technological innovation and start-up enterprises, are significantly changing people’s lives and work. Some of them improve people’s travel, some focus on saving social resources, and some are based on helping developers produce products … … The resultant force of all this has effectively promoted the economic and social development.

　　Innovation and entrepreneurship create a new situation of development

　　Over the past 30 years of reform and opening up, a number of outstanding innovative and entrepreneurial enterprises such as Huawei, Lenovo, Haier, Alibaba, Tencent and Baidu have been born one after another. A number of outstanding entrepreneurs such as Chen Chunxian, Ren Zhengfei, Liu Chuanzhi, Zhang Ruimin, Ma Yun, Ma Huateng and Li Yanhong have written one innovation and entrepreneurial legend after another.

　　Nowadays, China’s economy has entered the new normal of speed shift, structural adjustment, mode change and power change, and innovation and entrepreneurship have once again become a major reform measure to stimulate the wisdom and creativity of hundreds of millions of people, bringing together powerful new kinetic energy for economic and social development.

　　In recent years, China has introduced a series of policies and measures to encourage innovation and entrepreneurship, which have lowered the threshold for entrepreneurship and simplified the examination and approval process. The "one-yuan registered company", "multiple photos at one address", "three certificates in one" and "five certificates in one" have greatly reduced the cost of entrepreneurship. Encourage professional and technical personnel in universities, research institutes and other institutions to leave their posts to start businesses, release dividends from the reform of the science and technology system, encourage college students to start businesses, and provide policy support for specific groups to start businesses; Provide low-interest and interest-free loans for small and micro enterprises and provide tax relief policies; Encourage all localities to create service-related start-ups such as incubators, creative spaces and creative bases, and provide convenient services and financial support.

　　Currently, China’s 17 national independent innovation demonstration zones, 146 national high-tech zones, 2,530 science and technology business incubators, more than 2,300 creative spaces, 115 national university science parks, 2,688 productivity promotion centers, 453 national technology transfer demonstration institutions, and 71 innovative industrial cluster pilot and cultivation units. 391 national torch program characteristic industrial bases and 43 national torch program software bases have jointly formed a complete innovation and entrepreneurship service chain, created a good environment for innovation and entrepreneurship, and provided efficient, professional and comprehensive innovation and entrepreneurship services for enterprises in different stages such as innovation, seed incubation, entrepreneurship, growth and maturity. Entrepreneurship education, entrepreneurship training, exchange communities, angel investment, entrepreneurship incubation, entrepreneurship media, entrepreneurship competitions and other talents, laws, finance, advertising and marketing resources provide professional services for innovative entrepreneurs.

　　Various innovation and entrepreneurship policies and services have quickly become an important engine to stimulate the economy. Policy support, public participation and broad market have jointly promoted the emergence of entrepreneurial enterprises in China, and scientific and technological innovation has constantly subverted traditional industries. Many outstanding entrepreneurial enterprises have rapidly grown into the backbone of China’s economic transformation and made important contributions to China’s economic transformation and development.

　　Under such a big situation, "mass entrepreneurship and innovation" has become a new trend of the times, a powerful driving force for development, a powerful support for expanding employment, an important pusher for developing the sharing economy, a major innovation in the income distribution model, an effective way to promote social justice, and a "Chinese dream" bearing the prosperity of the country and the prosperity of the people.

　　At the same time, it should also be recognized that although China’s entrepreneurial activities are active in the global efficiency-driven and innovation-driven economies, and the entrepreneurial activity index is higher than that of developed countries such as the United States, Britain, Germany and Japan, the China report of Global Entrepreneurship Watch released in 2016 shows that the innovation content of China’s entrepreneurial activities needs to be improved, and "products adopt new technologies" (25.63, 50th) and "new markets" (24

　　Although China has achieved rapid economic development after more than 30 years of reform and opening-up, compared with major developed countries, China’s entrepreneurial environment conditions are not only the best in terms of physical infrastructure, but also in terms of financial support, government projects, education and training, research and development transfer, and business environment.

　　Especially under the background of increasing number of entrepreneurs and low success rate of entrepreneurship, it is necessary to carry out entrepreneurship education in depth to improve entrepreneurial ability and level. Improve entrepreneurs’ rational entrepreneurial awareness by identifying entrepreneurs’ quality education, and improve the success rate of entrepreneurship with the help of entrepreneurial tutors and the level of space service; Handle the relationship between the government and the market, and grasp the degree and quantity of government management and release. Avoid the bubble caused by excessively promoting the construction of entrepreneurial service carriers, and encourage the entrepreneurial failure behind entrepreneurship; We will steadily promote the popularization of internet plus and accelerate the integration of traditional industries and the Internet. Improve the service level of innovation and entrepreneurship carriers in internet plus, and focus on solving the problem of information asymmetry between entrepreneurs and entrepreneurial service carriers.

　　Edmund Phelps, a Nobel laureate in economics and a professor at Columbia University in the United States, stated in his book Great Prosperity that the prosperity of a society depends on whether the people in this society have the desire to participate in creating, exploring and meeting challenges. This kind of values has ignited the grassroots economic vitality necessary for independent innovation. Most innovations are not brought by Henry Ford’s lonely dreamers, but promoted by millions of ordinary people. It is this innovation of public participation that has brought prosperity to the common people — — The improvement of material conditions and the generalized "good life".

　　Create a new engine for development and enhance new impetus for development. Today, China is striding into the era of creation, and will witness more people participate in creation, exploration and dare to challenge, promote economic and social prosperity, strive to create a grand situation of mass entrepreneurship and innovation, and make new and greater contributions to the great rejuvenation of the Chinese nation.

In this year’s Spring Festival, seven films were released, covering comedies, science fiction, suspense, sports, animation, etc., which were richer and more diverse than in previous years.

According to the data of Lighthouse Professional Edition, as of 0: 10 on January 25th, the total box office (including pre-sales) of the Spring Festival in 2023 (January 21st-January 27th) exceeded 4 billion.

The ranking shows that Man Jiang Hong, Wandering Earth 2, Bears with Me and Bear Core are among the top three at the box office.

"Man Jiang Hong" and "Wandering Earth 2" are on the verge of a big box office battle.

During the Spring Festival, the audience is more willing to enter the cinema. In addition, this year’s Spring Festival file can be described as "the best in history". Every movie has the determination to win and started a box office war without smoke.

Among them, the best pre-sale and reputation is the excellent soft science fiction movie Wandering Earth 2.

With the support of big IP, starring Frant Gwo+Jason Wu+Andy Lau, and the first box office and word of mouth, it naturally occupied the first place in the box office list on the first day of release.

Before the official release, thanks to the basic advantages, the number of people who want to see Wandering Earth 2, the proportion of films arranged and the pre-sale box office are higher than that of Manjianghong. On the first day of "Wandering Earth 2" on New Year’s Day, the number of screenings was 115,000, accounting for 27%; On the first day of "Man Jiang Hong", the number of screenings was 110,000, accounting for 25.6%.

But the position of the movie Wandering Earth 2 is not unshakable. Facing the "strong enemy" — — The word-of-mouth of "Man Jiang Hong" directed by Zhang Yimou is constantly fermenting, and the box office trend and film arrangement of the film are also constantly changing. On January 24th, Manjianghong, which has a more friendly viewing threshold, overtook Wandering Earth 2. At present, the box office and box office forecast of the latter are higher than the former.

According to the data of Cat’s Eye Professional Edition, compared with the opening of the New Year’s Day, the box office record of the seven new films at this time has changed obviously. The movie Manjianghong surpassed Wandering Earth 2 in a single day, and Bears with Me "Bear Core" even surpassed Nobody to enter the top three. The movie "Man Jiang Hong" went down at the box office and even rushed to the hot search list.

In this regard, some people broke the news that the IMAX field, a special effects movie that should have played Wandering Earth 2, was filled with a non-special effects movie "Man Jiang Hong". Not only that, but also fans said that "Man Jiang Hong" stole the box office of "Nobody". On January 24th, the propagator of the movie "Man Jiang Hong" responded that the so-called "stealing box office" and "ghost field" of "Man Jiang Hong" was that someone deliberately hacked the film.

"China Table Tennis Jedi Counterattack" was difficult to break through at the box office yesterday.

The film China Ping-Pong’s Jedi Strike Back was influenced by many factors, and it was rescheduled from the first day of New Year’s Day to the third day of New Year’s Day. However, the overall situation of the Spring Festival has been decided. On the first day of its release, the sports film "China Ping-Pong’s Jedi Counter-Strike" had a box office of less than 50 million, with only 9.7% of the films arranged, and the attendance rate was only 14.5%, far lower than other films.

As a result, it has become the worst box office performance among the newly released films in the Spring Festival. At present, the professional version of Cat’s Eye Film predicts that China Ping-Pong will eventually have a box office of 250 million, which shows that the performance has been far below expectations.

Bears are still strong. The drama is not as good as the cartoon.

On the whole, this year’s Spring Festival box office drama is not as good as cartoons.

Parent-child group is still an important audience of the Spring Festival file. The animated film "Bear Haunted with Me" Bear Core "won the third place in the single-day box office, becoming the TOP3 in the same period with an expected box office of 1 billion+,and will also become the first 1 billion+movie in the series of animated IP.

From the perspective of return on investment, Bears with Me "Bear Core" is a cost-effective one, which also proves the importance of continuously cultivating IP value.

However, before its release, the animated film Deep Sea, the comedy Exchange of Life and the film Nobody with the top YiBo blessing failed to become dark horses.

From the word of mouth, "Exchange of Life" has been criticized as an embarrassment, far from reaching the level of Hi, Mom’s play. Although the collocation of Lei Jiayin and Zhang Xiaofei is innovative, it has been held back by the plot, and the counterattack after word of mouth fermentation may be extremely slim.

However, the movie atmosphere of The Unknown and Deep Sea does not match the image of "family fun" in the Spring Festival file, and the threshold of Guanyin is relatively high, and the possibility of counterattack is relatively low.

At present, the movie "Exchange of Life" has accumulated 236 million box office, and the final box office is predicted to be 369 million. The movie "Nobody" has a cumulative box office of 339 million, and it is predicted that the final box office will be 675 million; The movie Deep Sea has accumulated 218 million box office, and the final box office is predicted to be 612 million.

　　Author | Gao Xiaohong

　　Source | China Broadcasting Magazine (ID:zggbzz)

　　At present, China is facing the severe challenge of novel coronavirus (NCP or COVID-19 in English, COVID-19 in Chinese). The epidemic situation in COVID-19 is a particularly serious public health emergency, which greatly threatens people’s lives, health and safety. As of February 18th, 72,530 cases have been diagnosed, including 11,741 cases of severe illness and 1,870 cases of death.

　　On February 3, General Secretary of the Supreme Leader clearly pointed out at the The Politburo Standing Committee (PSC) meeting: "The current situation of epidemic prevention and control is severe and complicated, and some people have anxiety and fear. The propaganda and public opinion work should be intensified to coordinate online and offline, domestic and international, major and minor issues, better strengthen confidence, warm people’s hearts, gather people’s hearts, and better safeguard the overall stability of society."

　　In this critical period, "the news media is the main body of communication and responsibility of emergency reports, and undertakes important missions such as information communication, comforting people, supervising the government and mobilizing society". The domestic mainstream media, represented by the Central Radio and Television General Station (hereinafter referred to as the General Station), fully responded to the prevention and control of the COVID-19 epidemic, fought in the front line of fighting the epidemic, took the initiative to undertake the anti-epidemic mission of the mainstream media, timely released authoritative information, accurately reported the epidemic, responded to social concerns, grasped the "time effect", actively guided public opinion, and created a good public opinion atmosphere for rallying people’s hearts and enhancing confidence in fighting the COVID-19 epidemic. This paper focuses on the specific measures taken by the General Station during the fight against the COVID-19 epidemic.

　　01

　　Unblocked information:

　　Give full play to the authority and professionalism of mainstream media

　　1, timely, open and accurate report on the progress of the epidemic

　　The report of unexpected events refers to the news media’s integration of media resources in the process of the occurrence and development of events, and their reporting and evaluation of various situations related to events to the society and the public. After the outbreak of COVID-19 epidemic, a major public health event, the whole society paid close attention to the epidemic information and the progress of epidemic prevention and control. China quickly launched a Class I response to major public health emergencies, and the National Health and Wellness Commission and the health and wellness commissions of all provinces, autonomous regions and municipalities directly under the Central Government announced the epidemic information of infectious diseases in their respective administrative regions to the public. The information on epidemic situation of infectious diseases should be published in a timely and accurate manner. At the same time, the news media should also report the true information of emergencies in a timely and accurate manner according to the law, protect the people’s right to know, and contribute to the handling and aftermath of public emergencies.

　　Since the outbreak of the war of resistance against the epidemic, the general station has released authoritative information in time and continuously spread the epidemic situation around the clock. The News 1+1 column of CCTV, the general station, has been arranged as a whole and specially planned, and has continuously reported the COVID-19 epidemic since January 20th.

　　On January 20th, this column was connected with Academician Zhong Nanshan, the leader of National Health Commission high-level expert group, to introduce the basic situation of COVID-19 epidemic, which played a role of "setting the tone" in the information dissemination of COVID-19 epidemic. Since January 26th, CCTV News Channel of the General Station has launched "Special Report on the War Epidemic", with the theme of fighting the epidemic, continuously focusing on the national situation of fighting the epidemic, and releasing the latest data of the epidemic in time, so that people can know fairly well. It also connected with reporters from the front-line general station of the anti-epidemic in real time, showing the good mental state of all regions and departments in fighting the epidemic with one heart and one mind. At the same time, we will give full play to the advantages of the platform and share the program resources. From January 29, CCTV will broadcast CCTV programs simultaneously from 10: 00 to 11: 00 and from 15: 00 to 16: 30 every day.

　　In the reporting of major public health emergencies, the openness and transparency of information is very important. As a bridge connecting the government and the people, the mainstream media should disclose authoritative information at the first time and occupy the first place in the public opinion field.

　　From January 26th, the press conference of the State Council Press Office, National Health Commission Press Conference and the State Council Joint Prevention and Control Mechanism will be broadcast simultaneously by CCTV’s comprehensive channel and news channel, and broadcast simultaneously by China Voice. Every day, through the live broadcast of the press conference on epidemic prevention and control, the prevention and control information in COVID-19 can be disseminated openly and transparently, and the people’s right to know is fully respected and guaranteed. At the same time, speaking in a timely, active and rational manner has also curbed the spread of online rumors.

　　2. Interview authoritative sources and release authoritative information on epidemic prevention and control.

　　After the outbreak of COVID-19 epidemic, the spread of all kinds of information, especially the spread of new media space on the Internet, is very active, which makes the people contact with a lot of information every day, and the phenomenon of information overload appears. At the same time, the people are very concerned about the spirit of the central government and the policies, methods, and prevention and control process of epidemic prevention and control. Therefore, the mainstream media need to exert their authority and credibility and master the leading power of public opinion. This is also an initiative to set the agenda and master the right to publish, define and interpret issues. As the authoritative mainstream media in China, the reception desk gathers the advantages of interview resources by releasing official authoritative information at the first time, interviewing authoritative experts and frontline workers against the epidemic, and carefully sets the media agenda for fighting the COVID-19 epidemic.

　　3, professional team to fulfill the responsibility and mission of news propaganda work.

　　In the highly developed communication environment of online social media, the mainstream media put forward more stringent requirements for the authenticity, accuracy and security of information in this public opinion campaign against the COVID-19 epidemic. Because if the information is slightly deviated, it may cause the content to spread out of control, and then affect the credibility of the mainstream media.

　　On the one hand, the main station sent a professional team to the first scene to fight the epidemic, on the other hand, it strengthened the supervision of the contents of epidemic prevention and control to ensure the foolproof dissemination of information. From January 27th, the General Station set up the "Wuhan Live Studio of War Epidemic" in Hubei Radio and Television Station, and set the studio at the forefront of the fight against the epidemic. The broadcasting frequency of the main station gives full play to the emergency role of broadcasting in public health emergencies. By taking advantage of the advantages of wide broadcasting coverage, fast transmission speed and low listening threshold, the emergency reporting plan is launched at the first time, and the propaganda of epidemic prevention and control is intensified. All programs broadcast the progress of epidemic prevention and control in COVID-19 in a rolling way throughout the day. Every day from 19: 00 to 20: 00, the "Voice of China Special Report on Fighting the Epidemic" is also launched. During the week from February 3rd to 9th, there were 1,400 epidemic-related reports and nearly 7,000 written messages.

　　In 2018, General Secretary of the Supreme Leader pointed out in his speech at the National Conference on Propaganda and Ideological Work: "To do a good job in propaganda and ideological work under the new situation, we must consciously undertake the mission of raising flags, gathering people’s hearts, educating new people, rejuvenating culture and displaying image."

　　Since the outbreak of New Crown Pneumonia, the broadcast time of CCTV’s "News Network" program has been extended for many times, and the coverage of fighting against the COVID-19 epidemic has been increased, which reflects the professional mission and responsibility of the mainstream media, and its professional ability has been widely recognized by the society. On February 12th, Li Zimeng, the host of CCTV News Network, read the manuscript for 8 minutes without any jam, and the professional skills of news reporting were recognized by netizens. "Li Zimeng bowed his head and read the manuscript" was listed on the hot search list of Weibo, and on February 14th, the host Hai Xia broadcast for 12 minutes without any jam, and then went to Weibo for hot search ("Hai Xia bowed his head and read the manuscript"), and CCTV girls also boarded the hot search together, with the above three hot searches.

　　02

　　Enhance confidence:

　　Grasping "Time Effect" and Realizing the Effect of Public Opinion Guidance

　　1, the importance of public opinion orientation in the war epidemic.

　　When dealing with major public emergencies, the news media plays an important role in guiding public opinion. The General Secretary of the Supreme Leader pointed out, "It is crucial for the masses to know more about what the Party and the government are doing and what they need to do, so as to strengthen the confidence of the whole society and overcome the epidemic." At the critical moment in the fight against the epidemic in COVID-19, it is important for the news media to do a good job in guiding public opinion and grasping the correct direction of public opinion, which is conducive to rallying strength and inspiring people, guiding the public to rationally and correctly view and analyze the epidemic situation, scientifically taking preventive measures against the epidemic, and actively responding to the possible impact of the epidemic.

　　Past experience shows that public opinion guidance for major emergencies has basically established two footholds: one is to guide with facts, that is, to tell the public the truth; The second is to use value guidance, that is, to influence the public to look at the truth correctly. On the basis of timely, open and accurate reporting on the epidemic situation and its prevention and control information, the guidance of public opinion of news media should always focus on publicizing and reporting the important speech of the Supreme Leader General Secretary and the spirit of a series of important instructions, firmly win the determination and confidence to fight the COVID-19 epidemic, gather social consensus, adhere to the unity of party spirit and people’s nature, carry forward the main theme and stimulate positive energy.

　　All channels and frequencies of the main station use the all-media matrix to convey the spirit of the important instructions of the CPC Central Committee and the Supreme Leader General Secretary in time, give play to the public opinion power of the main station’s independent comments on the brand, actively interpret the signals of the central meeting, and strictly implement the decision-making arrangements of the CPC Central Committee. Commentators’ articles on epidemic prevention and control published by International Sharp Review show the world China’s determination and confidence to overcome the epidemic and meet the challenges. Commentators’ articles on epidemic prevention and control published by CCTV Quick Review have boosted morale and gathered strength in the propaganda and reporting on fighting the epidemic.

　　2. Grasping and innovating the principle of "time and efficiency"

　　The party’s news and public opinion work requires grasping the principle of "timeliness and effectiveness" and acting according to the law of news dissemination. Specifically, it is necessary to deal with the timeliness, rhythm, strength, discretion and effect of public opinion guidance.

　　In terms of timeliness and rhythm, the reception desk not only released the COVID-19 epidemic in time, but also realized real-time and full-time reporting, which responded to social concerns and met the people’s requirements and expectations for timeliness of epidemic information. At the same time, the reporters of the General Desk raced against the same time and went to the front line at the first time to interview the leaders of relevant institutions, publicly respond to the shortage of medical protective equipment and other issues, interview experts to fight the epidemic, and understand the work content of the front line of epidemic prevention and control and the treatment of severe and critically ill patients; Experts were also asked to answer the hot topics and questions of the masses, which met the deep-seated needs of the people for prevention and control knowledge in the context of the Internet.

　　In terms of the strength and discretion of news reports, the epidemic reports of the main station are of high frequency, high intensity and high quality, thus achieving high coverage of epidemic prevention and control information.

　　According to the data of CCTV Advertising Management Center, from January 24th to February 2nd, the viewing rate of News Network increased significantly, reaching 11.72%, and the viewing rate of viewers aged 15-24 increased by 186% year-on-year. The outbreak of COVID-19 epidemic coincided with the Spring Festival. With the escalation of prevention and control measures, the extension of the Spring Festival holiday, and the implementation of personal home prevention and control measures, radio and television, as a family-accompanying media, just played a key role in spreading anti-epidemic information in families.

　　In terms of the effect and actual effect of public opinion guidance, the general station boldly innovated on the new media platform by means of media integration, and achieved outstanding communication effects. For example, from 8: 00 on January 27th, CCTV News launched an uninterrupted live broadcast of the special program "Common War Epidemic", which was broadcast simultaneously on CCTV Video, CCTV News client, Tik Tok, Aauto Quicker and other mobile new media platforms, providing viewers with an information channel that directly hits the front line of epidemic prevention and control 24 hours a day. The reporter from the General Station visited the epidemic prevention and control site and made a comprehensive, accurate and timely report on the detection, diagnosis and treatment of patients in various regions, the work and living conditions of medical workers, and the production, supply and transshipment of medical protective equipment. The live broadcast attracted tens of thousands of viewers from all over the country to interact in real time, and "Come on Wuhan, Come on Hubei, Come on China" was screened.

　　At 19: 00 on January 31st, CCTV News Network entered the "Aauto Quicker" short video community and began the normal live broadcast. Within 33 minutes of the first live broadcast, the cumulative number of viewers was nearly 20 million. Since February 1st, "News Network" has been broadcast live on Sina Weibo, with a cumulative audience of 17.658 million, with an average daily audience of 1.358 million. In addition, CCTV news official Weibo initiated the topic of "real-time broadcast of joint prevention and control of epidemic situation", which was read 3.36 billion times and discussed 374,000 times, with a maximum reading of 608 million times in a single day. The topic of "common war and epidemic" has been read 6.07 billion times, discussed 1.55 million times, and the highest reading volume in a single day is nearly 870 million times. Through the way of integrated communication, the mainstream media has exerted great influence among young people and achieved the communication effect guided by public opinion.

　　3. Storytelling: Reflect the people’s determination and deeds in fighting the epidemic.

　　"People-centered" is an important working principle of the party’s news and public opinion work. In the report on the fight against the epidemic in COVID-19, the reception desk pointed the lens and microphone of news reports at the people’s anti-epidemic actions. By recording touching stories and accumulating ordinary materials, it told the stories of people around us and described the greatness of ordinary people, conveyed the warmth of humanity and humanistic care behind the severe epidemic, and showed the spirit of the people of the whole country to unite as one and help each other in the same boat.

　　On January 29th, the Voice of China, the Central Broadcasting Station, launched the special program "Diary of an Angel". The content of this program comes from angels in white who are facing the COVID-19 epidemic and racing against death. It records the daily work of front-line medical staff in the form of voice self-report and first-person perspective. Angel Diary broadcasts an episode every day, and at the same time, it is launched on Himalayan FM audio platform, and published on Voice of China Weibo and WeChat WeChat official account. The program gives full play to the voice advantage of broadcasting, and spreads the positive energy story of fighting the epidemic with a keen perspective and delicate brushwork. According to the data, its single item in Weibo received the highest praise of 19,000 person-times, and the cumulative reading volume of WeChat WeChat official account exceeded 344,000 person-times.

　　In addition, since February 11th, News Network has launched a column "A Line of Anti-epidemic Groups" to report the effectiveness of joint prevention and control measures by various departments in various regions and tell touching stories about the front line of anti-epidemic. The book "Wuhan at Zero, Here are Stories You Don’t Know" by feature story of the Central Broadcasting Corporation truthfully records the voices of people in Wuhan in the middle of the night and bears witness to the determination and persistence of people from all walks of life. By reporting the great love and responsibility of front-line workers, the mainstream media has established an emotional bond for the people to overcome the difficulties together.

　　03

　　Stabilizing People’s Heart: Facing the Social Concern of Major Public Emergencies

　　1, timely counseling to resolve the crisis of public opinion.

　　The prevention and control of the epidemic situation in COVID-19 is all-round. In the field of news and public opinion, the first problem is to face and promptly dispel the possible public opinion crisis. The so-called public opinion crisis refers to the phenomenon that public opinion is at a difficult juncture because unfavorable public opinion occupies the central position in the public opinion field. In order to avoid and prevent the public opinion crisis and smoothly resolve the contradictions and problems caused by unexpected events, it is necessary to open the way, promptly guide and master the initiative.

　　After the occurrence of major public emergencies, the news media should fully predict the current public opinion environment, and make adjustments from the perspective of overall information dissemination, ensure the expression of opinions of the masses, reflect their voices, channel negative and negative public opinion, and encourage and advocate positive public opinion.

　　The outbreak of the COVID-19 epidemic coincided with the Chinese Lunar New Year, so the festive atmosphere became heavy, and the people’s life focus shifted to preventing and controlling the COVID-19 epidemic and ensuring life safety. In this public opinion environment, the reception desk immediately made adjustments, and the 2020 Spring Festival Gala broadcasted a scenario report program "Love is a Bridge" with zero rehearsal. Through the form of scenario narration, it showed the touching scene of Wuhan people facing up to the sudden COVID-19 epidemic and the medical staff selfless treatment.

　　Later, in the recording of the Lantern Festival special program, we dug deep into the first-line story of epidemic prevention and paid tribute to the "most beautiful retrograde" who silently contributed to the epidemic prevention work, showing the great cohesion of the Chinese nation and the spiritual strength of the people of the whole country to work together to overcome difficulties, which was well received by the audience.

　　According to statistics, as of 10: 00 on February 5th, the epidemic news materials released by CCTV International Vision and the press conference signals held by state authorities were selected and broadcast by 1,721 overseas TV stations or channels in 112 countries and regions, including Fox and BBC, for more than 362,000 times, which won wide respect and support from the international community.

　　2. Relieve public panic.

　　After the outbreak of the epidemic in COVID-19, especially at the initial stage of the outbreak, the public was in a state of panic due to the fact that the focus of the epidemic has yet to be scientifically studied, the situation of epidemic spread is grim, the effect of epidemic prevention and control has yet to be observed, and the drugs for treating and preventing the epidemic have yet to be developed. The public’s panic is manifested in various ways, such as the spread of rumors and rumors, weak awareness of scientific prevention and group prevention and control, and panic buying of masks and medical supplies in some areas. During the prevention and control of COVID-19 epidemic, it is very important for the mainstream media to play the role of public opinion guidance to alleviate public panic. Previous studies have shown that if we can correctly use the guiding function of the mainstream media, we can promote the original absurd rumors to become a "pedal" for people to understand the truth and scientific knowledge.

　　On the basis of interviewing authoritative sources and releasing authoritative information on epidemic prevention and control, the Headquarters also launched a series of promotional videos in conjunction with the Propaganda Department of National Health Commission to popularize the knowledge of COVID-19 epidemic prevention and guide the public to enhance their awareness of self-prevention. Each of these popular science videos is about 1 minute long, which effectively and conveniently spreads the practical operation and prevention and control concepts of legal prevention and control, scientific prevention and control, and group prevention and control, and the communication effect is good. Up to now, the series of public service short films have landed on nearly 400,000 digital screens in 50 cities across the country, playing circularly at major airports, stations and ports, and landing in business districts, communities, enterprises and universities in Beijing, Shanghai and other cities.

　　In the communication environment of media convergence, the new comprehensive audio-visual media flagship "Central Video" 5G new media platform newly built by CCTV based on new technologies such as "5G+4K/8K+AI" was officially launched not long ago, which was put into the prevention and control propaganda of the COVID-19 epidemic. CCTV, the main station, opened up "War ‘ Epidemic ’ The topic "Frontline" includes vlog real shooting, exclusive interview, scientific inquiry, suggestions, real-time panorama and other sections. Record the true story of the "epidemic" front line, follow up the latest progress of experimental research and development, and introduce the knowledge of epidemic prevention science in the form of short video; "CCTV News" broadcasts "Common War" 24 hours a day, and works with hundreds of millions of viewers to supervise, watch, accompany and guard the cloud.

　　On the evening of January 27th, CCTV opened a 24-hour live broadcast port, and started the "slow live broadcast" of the construction of Huoshenshan Hospital and Thunder God Mountain hospital through the 5G+ optical fiber dual Gigabit network, and multiple aircraft seats presented live real-time pictures around the clock. Without the host, commentary and editing and packaging, it attracted nearly 120 million online "cloud supervisors". The series of live broadcasts were broadcast on 11 online platforms, including Tencent News, Today’s Headlines, Phoenix News, Youku and Wo Video. The total number of viewers exceeded 15 million and the number of interactive comments exceeded 13,000. The series live broadcast and slow live broadcast are broadcast on CCTV News client, @ CCTV News Weibo, CCTV Video client and Tik Tok, Aauto Quicker and Betta Fish. Among them, only the short video of "Tik Tok" was watched by more than 55 million people.

　　These measures not only mobilized the people’s initiative and sense of participation in the prevention and control of the epidemic in COVID-19, but also helped the people to relieve their anxiety and panic in the high-intensity and fast-paced information environment through the relatively gentle "slow live broadcast".

　　3. Carry out constructive news supervision by public opinion.

　　The General Secretary of the Supreme Leader pointed out: "This epidemic is a big test of China’s governance system and ability. We must sum up experience and learn lessons." "In the epidemic prevention and control work, formalism and bureaucracy have appeared in some places." The General Secretary of the Supreme Leader also stressed that "authoritative information should be released at multiple levels and at high density, existing problems should be faced squarely, the concerns of the masses should be responded, timeliness, pertinence and professionalism should be enhanced, and the masses should be guided to enhance their confidence and strengthen their confidence, and efforts should be made to stabilize public sentiment." In the process of epidemic prevention and control in COVID-19, the mainstream media actively responded to public concerns, reflected the problems existing in the governance process, especially in the epidemic prevention and control work, played the role of constructive public opinion supervision of the news media, and promoted the epidemic prevention and control work.

　　On January 29, the Central Steering Group sent an inspection team to Huanggang City, Hubei Province, where the epidemic was serious, for supervision and verification. CCTV reporters covered the whole process. In the report, the working ability of the person in charge of the local competent department was questioned. After the news broadcast, the role and effect of public opinion supervision were produced, and the director of the health and health commission in Huanggang City was immediately dismissed. In the supervision of news and public opinion, the mainstream media always adhere to the problem orientation, which can neither make a mountain out of a molehill to cause panic, nor make a mountain out of a molehill to make the work lax. We should correctly carry out constructive public opinion supervision, meet the audience’s higher-level pursuit of information disclosure in the all-media environment, and promote the solution of problems in the prevention and control of epidemic situation in COVID-19.

　　The whole people participated in the war against the COVID-19 epidemic, and the effect was obvious. Under the situation of unified and centralized leadership of the CPC Central Committee, mobilization and participation of the whole society, and comprehensive prevention and control, the battle of epidemic prevention and control will surely win the final victory. At the critical stage of epidemic prevention and control, the authoritative mainstream media, represented by the Central Radio and Television General Station, adhered to the duty and mission of news and public opinion work, gave full play to the authority and professionalism of the mainstream media, grasped the principle of "time and effect" and carried out news and public opinion work "people-centered", which unblocked information, enhanced confidence and stabilized people’s hearts.

　　The author of this paper is Gao Xiaohong, Minister of Journalism and Communication at China Communication University, and distinguished professor, a Changjiang Scholar at the Ministry of Education. Cai Yu is a Ph.D. student at China Communication University, originally published in the third issue of China Broadcasting in 2020.

Interview video

Interview site

Lu Mingxia, Director of Monitoring Room 1, Institute of Immunization Planning, Henan CDC

　　Vaccination is the most direct and effective measure to prevent infectious diseases. National Health Commission recently published "Procedures and Instructions for Children’s Immunization under the National Immunization Program (2021 Edition)", which made the latest planning and adjustment on vaccination age, vaccination site, replanting principle and other contents. On the afternoon of March 18th, Lu Mingxia, director of the first monitoring room of the Institute of Immunization Planning of the Provincial Center for Disease Control and Prevention, made a guest visit to the online interview program of Henan government website to interpret the new national immunization program and introduce the vaccination situation of children in Henan province.

　　There are four changes in the new immunization program, and the supplementary vaccination of children is extended to 18 years old.

　　"Vaccination is the most direct, effective and economical measure to prevent infectious diseases, and immunization planning vaccine refers to the vaccine that is vaccinated for school-age children free of charge according to national procedures, and it is also a vaccine that must be vaccinated." Lu Mingxia introduced that the National Immunization Program for Children (2021 Edition) is the latest version of the children’s immunization program in our country. Compared with 2016, there are four main changes.

　　First, the age of replanting is prolonged. The age range of coverage has been expanded from 14 years old and below to 18 years old. On the one hand, the definition of adults in China is over 18 years old, and on the other hand, it has laid a foundation for promoting vaccination and replanting of adolescents in the future.

　　The second is to clarify the inoculation site. When a variety of vaccines are inoculated at the same time, they can be inoculated in the left and right arms and the left and right thighs respectively, which is more specific than the 2016 version of "Two or more vaccines should be inoculated in different parts".

　　Third, the use of vaccines is more operational. For example, in the part of hepatitis B vaccine, it is more operable to vaccinate newborns and low-birth-weight infants born to mothers with positive or unknown hepatitis B surface antigen, and in the part of BCG, the principle of BCG vaccination for premature infants has been added.

　　Fourth, the vaccination guidelines for children with special health status have been added. Detailed guidelines are defined for vaccination of children with premature delivery, low birth weight, allergy, abnormal immune function, jaundice, liver disease, encephalopathy and common congenital diseases.

　　"In short, the new national immunization program is more detailed, which is conducive to the implementation of vaccination doctors and the healthy growth of children." Lu Mingxia said.

　　Vaccination should be kept on time and throughout the whole process.childrenVaccination certificate

　　According to Lu Mingxia, since 1978, the state has been vaccinating people in a planned way to prevent infectious diseases. According to the needs of infectious disease prevention and control, the content of children’s immunization program has been increased and adjusted several times. At present, there are 11 kinds of vaccines for children in Henan Province to prevent 12 kinds of infectious diseases, that is, "11 vaccines against 12 diseases". "There are more than 1 million newborns born every year in the province, and the vaccination rate is over 90%. An immune barrier has been established among the population. The incidence of these 12 vaccine-targeted infectious diseases is very low, such as polio, also known as polio. There have been no cases in Henan for 28 consecutive years."

　　Lu Mingxia reminds parents that vaccine is the best health gift for their children. They should take their children to be vaccinated in time and vaccinate them on time and in the whole process according to the provisions of immunization procedures. If you miss the vaccination time for special reasons, it will increase the risk of disease exposure, and replant it in time when conditions permit. In addition, we must keep the vaccination certificate well, so as not to affect children’s normal attendance at kindergarten and primary school. (Text/Yin Xinyu Zhu Ping Zhao Meng Camera/Mu Yu Wang Shuangfei Jia Zhihao Clip/Jiang Yuxi)

　　Correspondent Tang Tang Our reporter Zhang Wei

　　When people get sick, they often have to hang water to take medicine. However, after the drug enters the human body, it is not smooth sailing to reach the designated position, stay for a longer time, be better absorbed, and avoid being accidentally injured by friendly forces.

　　In recent 20 years, more and more new nano-pharmaceutical preparations have flooded into the market, and nano-liposomes with the name of "small steamed buns" in the carrier have emerged as the times require. This kind of vesicle with nanometer particle size formed by lipid bilayer can wrap drugs with great toxic and side effects, poor stability and rapid degradation. By fusing with the cell membrane, the carried drugs are concentrated in the focus, so as to achieve targeted administration, and at the same time, the curative effect can be improved, the toxicity can be reduced, and the stability can be enhanced.

　　Recently, Professor Gu Ning of Southeast University led a team to break the technical barriers abroad, overcome the key technologies of nano-lipid materials, built the first domestic and largest production line of lipid nanoparticles in the world, and won the first prize of scientific and technological progress in Jiangsu Province.

　　Then, how does this nano-scale "little one" take on the heavy responsibility of "packaging" and "transporting" through-train service? What other unknown uses do nanoliposomes have besides their great potential in drug carriers?

　　Known as the secret weapon of "rejuvenation"

　　The formation of liposomes is due to the self-assembly properties of a substance called phospholipids. Phospholipid is an amphiphilic substance, one end is hydrophilic and the other is lipophilic. Due to the particularity of its molecular configuration, phospholipid will spontaneously assemble into a bimolecular membrane structure in water, and part of it will be wrapped inside, which is usually called "vesicle".

　　The earliest liposomes were naturally formed in water. After scientists discovered its special skills, they tried to synthesize phospholipid compounds by artificial methods in order to achieve the purpose of mass production. The diameter of liposomes is usually tens of nanometers to tens of millimeters, and "nano-liposomes" are liposomes with nanometer particle size.

　　The membrane structure of lipid nanomaterials is very close to the cell membrane, which provides convenience for drug delivery and absorption. Therefore, liposomes can wrap the effective components and introduce them into cells, so that the effective components can easily enter cells.

　　In many common drugs, liposomes are responsible. Such as antineoplastic drugs, drugs targeting reticuloendothelial system, protein and nucleic acid drugs, antibacterial drugs, anti-inflammatory hormone drugs, etc. Moreover, the drug with liposome as the carrier "skin is not delicate" can be administered in any way, including intravenous injection, subcutaneous and intramuscular injection, oral administration, pulmonary administration and skin administration.

　　"The size of liposomes is related to the route of administration and drug release rate, but nano-sized liposomes have obvious advantages as drug carriers." Professor Gu Ning told reporters that daunorubicin liposomes, for example, have a particle size of 60-mdash; 120 nm, because of its small particle size, it is not easily recognized by phagocytes of reticuloendothelial system after entering the blood circulation, so it can stay in the blood circulation for a long time. At the same time, the pharmaceutical preparation has no obvious cardiotoxicity.

　　In recent years, more and more nanoliposome drugs have flooded into the international market and become the fastest-growing high-end pharmaceutical preparation in the world. Nanoliposomes not only play an important role in the pharmaceutical industry, but also act as a professional "courier" in cosmetics. It can keep the activity of cosmetics well, so that growth factors and other ingredients can enter the stratum corneum faster and more completely, thus enhancing the cell repair ability. Therefore, liposome encapsulation is known as the secret weapon of "rejuvenation".

　　Oil-loving and hydrophilic "amphiphilicity" increases the difficulty of mass production

　　In recent years, in the international pharmaceutical field, dexterous and multifunctional nanoliposomes have almost become "online celebrity".

　　At present, a total of 29 nanoliposome drugs have been approved for marketing in the world. In addition, there are 87 nanoliposome drugs in clinical research stage and 132 nanoliposome drugs in preclinical research stage. Among them, there are 13 nanoliposome drugs approved for marketing by the US Food and Drug Administration (FDA).

　　In sharp contrast, only three nanoliposome drugs in China have been approved for production, namely paclitaxel liposome for injection, doxorubicin hydrochloride liposome and amphotericin B liposome for injection.

　　But 10 years ago, the related drugs and cosmetics in China were blank, and the people in China could not touch them at all, because the key technologies of lipid nanomaterials were in the hands of foreigners.

　　The international market share of nanoliposome drugs is increasing year by year, but the industrialization development in this field in China has been slow. "The reason is that the lipid nanomaterials needed by nanoliposome drugs are completely imported, and their prices far exceed the raw materials themselves; Second, the quality, purity and stability of domestic liposome pharmaceutical preparations need to be improved; Third, the assembly technology of lipid nano-materials and the preparation technology of lipid nano-drugs have high requirements and great difficulties. " Professor Gu Ning told reporters.

　　In 1970s, when liposomes were first used as drug carriers, they were once ignored because of their extremely unstable structure and low drug encapsulation efficiency. With the in-depth study of liposomes, the existing problems have been solved initially. In the early 1990s, economical and efficient anti-fungal and anti-cancer drug liposomes were put into the market, which greatly promoted the research and development of liposomes.

　　Lipid nano-materials have unique hydrophilic and lipophilic "amphipathy", which makes it possible to add lipophilic and hydrophilic drugs and active ingredients to the same drug at the same time.

　　However, researchers have also found that the amphiphilic nature of lipid nanomaterials is a double-edged sword, which not only provides convenience for drug loading, but also increases the difficulty of mass production. Therefore, the preparation process of lipid nano-materials is complex, which makes it difficult to remove impurities, and it is difficult to purify intermediates and products, so it is difficult to achieve mass production.

　　It is also a treasure to use "the wind blows on both sides"

　　The raw materials for preparing nanoliposomes are not complicated, but if you can’t master the doorway, you can’t make qualified nanoliposomes.

　　Well-made liposomes have a phospholipid bimolecular shell, which is very similar to the structure of cell membrane, and they are very small, and their diameters are basically below 150 nanometers, which is helpful for the penetration of active substances.

　　To realize the localization of lipid nanomaterials, the synthesis process is particularly important. Therefore, Professor Gu Ning’s team put forward an innovative new process for synthesis and purification of lipid nanomaterials. Through self-made separation filler and independent separation and purification technology, they realized the industrialization of high-purity lipid nano-medicinal carrier materials.

　　Lipid nano-materials are hydrophilic at one end and lipophilic at the other, which seems to be "the wind blows on both sides", so how to use them well is also very particular. After repeated experiments, researchers finally found a "trick up my sleeve". "We creatively put oil-soluble drugs on the oleophilic outer layer and water-soluble drugs on the hydrophilic inner layer, giving full play to the role of drugs, and truly fostering strengths and avoiding weaknesses." Professor Gu Ning said.

　　According to Professor Gu Ning, they developed a new process for the synthesis and purification of lipid nanomaterials, which used a "one-pot" reaction to prepare key intermediates, and the yield was doubled. At the same time, the liposome coordination technology broke through the key bottleneck of the assembly of glycyrrhizic acid drug phospholipid complex. Diammonium glycyrrhizinate was complexed with phosphatidylcholine, a lipid material, to form a lipid complex, which greatly improved the lipophilicity of glycyrrhizic acid and made it easier to cross the multiple membrane structures of the digestive tract and enter the blood circulation, effectively solving the problem of low oral bioavailability of glycyrrhizic acid.

　　After the success of the project, the price of domestic lipid nano-materials dropped significantly, which significantly reduced the overall cost of liposome drugs. In addition, lipid nanoparticles technology has been widely used in domestic first-line cosmetics companies, and it has played a great role in preparing cosmetics with whitening, anti-aging and wrinkle removal functions.

1905 movie network news　A few days ago, the film was scheduled for the New Year’s Day in 2021 and returned to the Spring Festival file. The discussion and expectation of movies on various platforms have been climbing all the way, and the ticketing platform has been constantly refreshed. The netizens are excited to comment: "I finally wait for you!" When Detective Chinatown 3 returned from new york, he was happy to visit Tokyo. Both the production and the lineup were upgraded in an all-round way.

Masami Nagasawa

As early as the end of the film, director Chen Sicheng planted the seeds of the third stop in Tokyo, and Tsumabuki Satoshi played Japanese detective Noda Hao, calling Tang Renhe and Qin Feng for help. When the audience finished watching it, they spontaneously left a message under the Detective Chinatown 3 movie item in advance, "If only there were Masami Nagasawa … …” I thought it was an unrealistic wish, but unexpectedly, the Asian goddess really came! As one of the most popular Japanese actresses in China, the joining of "Ma Jiang" Masami Nagasawa surprised fans. A half-joking comment in 2018 turned out to be a dream come true. Masami Nagasawa once said in an interview that he likes Tang Tan 2 very much, which has China’s unique sense of joy and joy, and the script of Tang Tan 3 is more attractive. With its powerful IP power, the "Tang Detective" series attracts the best filmmakers in the world.

Netizens expect Masami Nagasawa to join.

Other actors in Detective Chinatown 3 are equally heavy, including Starlight Glimmer, the Asian All-Star Team. Tsumabuki Satoshi, an old friend and starring in Tang Tan series; Tony Jia, the most famous action star in Thailand, has been exporting super-hot dramas in series and other films; Shōta Sometani who contributed a wonderful performance in the film; Honami Suzuki, who plays the role of Li Xiang and creates the memory of the times; As well as powerful actors Tadanobu Asano and Tomokazu Miura, will gather in Tokyo to meet the ultimate secret room problem.

Among them, Japanese detective Tsumabuki Satoshi and Thai detective Tony Jia, together with Wang Baoqiang and Haoran Liu, formed the "Asian Detective Union" to solve the most difficult cases since the Tang Detective Series. The four detectives have different cultural backgrounds, skills and personalities. They love each other and kill each other all the way, and they collide with more jokes. "They want to laugh when they stand together." Can the new "Asian Detective League" solve the puzzle and find the mysterious Q, and what role will the goddess Masami Nagasawa play? Detective Chinatown 3 meets you on the first day of 2021!

In the autumn season, the vast fields are full of bumper harvests.

In the rice fields of Qing ‘an County, Heilongjiang Province, the combine harvester shuttles back and forth, and the golden rice keeps flowing into the grain truck. "Big base with big equipment, fast and good. There are more than 1.3 million mu of rice in the county, and the comprehensive mechanization rate of field operations is 96.8%. " Fan Jun, director of Qing ‘an Agricultural Technology Extension Center, said.

Zhengyang Lu Hua Luzhou-flavor Peanut Oil Co., Ltd. in Zhengyang County, Henan Province, the automatic production line keeps running, producing 6,000 barrels of fine peanut oil per hour. "From selling raw materials to selling products and brands, the county has built a peanut industry chain covering planting, deep processing, futures delivery, spot trade and cultural tourism." Guan Xia, director of the Agricultural and Rural Bureau of Zhengyang County, said.

General Secretary of the Supreme Leader pointed out during his inspection tour in Jiangxi: "Insist on developing agriculture through industry, quality and green, and make agriculture a big industry". During his inspection tour in Heilongjiang, the Supreme Leader stressed: "We should take the development of modern agriculture as the main direction, speed up the construction of modern agricultural bases, large enterprises and large industries, and take the lead in realizing the modernization of agricultural materials and equipment, science and technology, management and management, agricultural informationization and sustainable utilization of resources."

This year is the first year to fully implement the spirit of the 20th National Congress of the Communist Party of China, and it is a crucial year to comprehensively promote rural revitalization and accelerate the construction of an agricultural power. Under the strong leadership of the CPC Central Committee with the Supreme Leader as the core, China’s agricultural modernization has made great progress, with abundant crops for planting, flourishing animal husbandry and six kinds of livestock, and the development of rural characteristic industries. The broad masses of cadres and people have worked hard to make agriculture a big industry and realize agricultural and rural modernization at an early date.

Construct a high-quality and efficient diversified supply system to ensure the stable and safe supply of grain and important agricultural products.

General Secretary of the Supreme Leader stressed: "No matter how high the degree of social modernization is, the stable supply of food and important agricultural products for more than 1.4 billion people is always a top priority."

To build agriculture into a big industry and build a diversified supply system with high quality and high efficiency, we must first firmly hold the rice bowl in our own hands.

In the harvest season, Huang Siwen, a large grain grower, is grabbing rice in the high-standard farmland of Sangtian Town, Nanfeng County, Jiangxi Province. "This year, 2,500 mu of mid-season rice was planted, and the yield per mu was about 1,300 Jin." Huang Siwen said, "The grain subsidy was put in place in time, the agricultural technology guidance went straight to Tiantou, and the’ big iron cow’ helped the whole process. This year is another bumper harvest year."

There must be strong support behind big bases and big equipment.

Strong policy-the state has improved the "trinity" policy system of price, subsidy and insurance, issued a one-time subsidy of 10 billion yuan to actual grain farmers, and the central government timely issued agricultural disaster prevention and relief funds … The policy measures are solid, stable expectations and strong confidence.

Strong science and technology-improved varieties are planted, good farming methods are used, and agricultural machinery is galloping. The contribution rate of agricultural science and technology progress in the country has reached 62.4%, the coverage rate of improved varieties of crops has exceeded 96%, and the comprehensive mechanization rate of crop cultivation has exceeded 73%. From "knowing how to farm" to "cultivating wisely", "golden pole" has continuously injected new kinetic energy into modern agriculture.

Strong foundation-high-standard farmland construction, black land protection, and high-yield demonstration area creation take a multi-pronged approach. Oda has become a big field, and "dividends" have been continuously released. By the end of 2022, a total of 1 billion mu of high-standard farmland had been built in China, which ensured a stable grain production capacity of more than 1 trillion Jin.

Strong service-planting good land and increasing grain production, financial support is indispensable. With the increasing financial support for agriculture, rural areas and farmers, financial institutions have also increased credit support. In the first three quarters of this year, the Agricultural Bank of China invested more than 200 billion yuan in loans in key grain areas.

Strong support brings steady development. China’s grain production has been bumper year after year, and the total output has been stable at more than 1.3 trillion Jin for eight consecutive years. According to the agricultural dispatch of the Ministry of Agriculture and Rural Affairs, as of October 22nd, the national autumn grain harvest has reached 81.3%, and the increase of autumn grain production is a foregone conclusion, and the annual grain output is expected to hit a new record high.

Ask for food from the forest, from rivers, lakes and seas, and from facility agriculture. Build agriculture into a big industry, coordinate grain, economy, feeding, agriculture, forestry, animal husbandry and fishing, and build a diversified supply system with high quality and high efficiency.

In the Gobi Eco-agricultural Industrial Park in Suzhou District, Jiuquan City, Gansu Province, vegetables and melons are full of vitality. Qin Cunguo, a vegetable grower, said: "Since the automatic control equipment of water and fertilizer integration was used, irrigated land has become irrigated seedlings. The average water consumption per mu is nearly half that of Datian, saving water and increasing production, and fresh vegetables are kept in the four seasons. "

Gao Fuliang, a farmer in Qiantang Village, beside the fish pond in Yuyue Town, Deqing County, Zhejiang Province, said: "With the continuous upgrading of fish pond facilities and the new green farming technology, the water is good and the fish grow better."

According to local conditions, based on resource endowment, all localities give full play to their comparative advantages. In addition to more than 1.9 billion mu of cultivated land, more than 4 billion mu of woodland, nearly 4 billion mu of grassland and a large number of rivers, lakes and seas have gradually become an important part of the diversified food supply system.

Facility agriculture has contributed a lot. At present, the planting area of modern facilities in China has reached 40 million mu, and about 70% of meat, eggs and milk and 52% of cultured aquatic products are provided by facility farming.

Extend the industrial chain, upgrade the value chain and expand the space for agricultural development.

Industrial revitalization is the top priority of rural revitalization.

When General Secretary of Supreme Leader presided over the symposium to promote the comprehensive revitalization of Northeast China in the new era, he pointed out: "Cooperate to promote the primary processing and intensive processing of agricultural products, extend the industrial chain, upgrade the value chain, expand the space for agricultural development, and promote agricultural efficiency and farmers’ income."

To build agriculture into a big industry, we should ponder over the word "native products" and build an agricultural industrial system with integrated production, marketing and sales.

Chestnut mushrooms grow just right in the greenhouse of Shanghegu Food Co., Ltd. in Qianxi County, Hebei Province. Zhang Jixiao, the person in charge of the company, said: "From planting chestnuts to planting chestnuts and mushrooms, the company is planning to build a production and processing base to extend the industrial chain of chestnuts."

The data show that the total cultivation of edible fungi industry in Qianxi County, mainly chestnut mushrooms, reached 100 million sticks, and the annual output of fresh mushrooms was 20,000 tons, achieving an output value of nearly 400 million yuan. A variety of chestnut powder, chestnut cakes and so on are also listed in hardcover. The cultivation area is 750,000 mu, the annual output is 80,000 tons, and the brand value is 3.409 billion yuan. Small chestnut has grown into a big industry moving to the west.

Looking at the whole country, the countryside is suitable for industry and the industry is prosperous. Relying on the characteristic resources, all localities have transformed the advantages of rural resources, ecology and culture into the advantages of products and industries, and formed a number of "township name" and "local name" brands, and made great articles on local products. Up to now, China has built 300 national modern agricultural industrial parks, 180 industrial clusters with advantages and characteristics, and 1,509 towns with strong agricultural industries, and the conversion rate of agricultural products processing has reached 72%.

The relevant person in charge of the Ministry of Agriculture and Rural Affairs said: "In the future, the construction of agricultural industrial chain will be further strengthened, and efforts should be made in R&D, production, processing, storage and transportation, sales, brand, experience, consumption and service to comprehensively improve the stability of the industrial system, and take multiple measures to expand the space for agricultural value-added and efficiency, strengthen the industrial chain, and improve the system of increasing income with agriculture."

To build agriculture into a big industry, it is necessary to cultivate new industries and formats in rural areas, promote agricultural efficiency and increase farmers’ income.

At the live broadcast base of e-commerce industrial park in Ningling County, Henan Province, the live broadcasters are recommending various agricultural products to netizens, and the atmosphere is hot. In the nearby logistics sorting center, workers are busy packing and loading cars to transport all kinds of agricultural products to various places. With the help of more than 1,000 online stores in the e-commerce industrial park, the annual sales volume of Ningling crisp pears has exceeded 100 million Jin. Not only do pears sell well, but also tourists come in droves.

New industries and new formats activate the great potential of rural industries. There are more than 300,000 leisure agriculture business entities in China, and the annual operating income exceeds 700 billion yuan. There are more than 30,000 e-commerce companies involved in agriculture, and the retail sales of rural networks exceed 2 trillion yuan. The deep integration of the primary, secondary and tertiary industries in rural areas will drive more farmers to achieve local employment. In the first three quarters of this year, the per capita disposable income of rural residents was 15,705 yuan, a real increase of 7.3% after deducting the price factor.

Develop moderate scale operation and speed up the improvement of agricultural socialized service system

Agricultural modernization is inseparable from the innovation of production and management methods.

General Secretary of the Supreme Leader stressed: "Developing moderate-scale operation is the direction of modern agriculture" and "accelerating the improvement of agricultural socialized service system, serving and driving small farmers well".

Innovate agricultural management system and mechanism and develop moderate scale management.

300,000 mu of peppers in Bozhou District, Zunyi City, Guizhou Province entered the harvest season, and pepper farmers were busy. "This year, 40 acres of peppers have been planted, and more than 10,000 kilograms have been sold, and the market is not worried." He Congwei, a villager in Yuanzi Village, Tiechang Town, picks peppers every morning and sends them to the processing workshop in the village.

This workshop is an important part of the order mode of "company+village collective+cooperative+village workshop+farmer". "From seed supply to technical guidance, field management to acquisition, we provide farmers with a’ one-stop’ service. At present, the daily purchase of peppers reaches 200 tons." Tang Songbai, deputy general manager of Guizhou Zhuohao Food Co., Ltd. said.

"Based on the basic national conditions and agricultural conditions of small farmers in big countries and accelerating the modernization of agriculture and rural areas, we should put innovative agricultural management systems and mechanisms in a prominent position, and improve agricultural scale benefits from two dimensions: cultivating new agricultural management entities and developing agricultural service outsourcing markets." Ye Xingqing, Minister of Rural Economic Research Department of the State Council Development Research Center, said.

Looking at the whole country, more than 4 million family farms and 2.22 million farmers’ cooperatives are actively exploring in the fields of improved seed breeding and promotion, green unified prevention and control, standardized production, etc., driving farmers, connecting markets, leading development, and promoting the continuous improvement of agricultural intensification, specialization, organization and socialization.

Strengthen the ability of agricultural socialized service and solve the production problems that one household can’t do it, can’t do it well, and can’t do it cost-effectively.

"1,000 mu of soybeans are entrusted to Beidahuang Agricultural Service Group, which is planted in two rows and close planting. One mu of land can be 70 kg higher than its own production, saving effort and increasing production." Lu Chunfeng, a villager from Xingfu Village, Xingfu Town, Suihua City, Heilongjiang Province, said.

The socialized service of Beidahuang Agricultural Service Group is not only effective on a large scale and in a large area, but also applicable in the south, which is good at intensive cultivation. Xiaogang Village, Fengyang County, Anhui Province, through the method of field transformation, the average field area has reached 27 mu, and unmanned transplanting can also be realized. The socialized service area of Beidahuang Agricultural Service Group has reached 78 million mu, and the service has driven 3.5 million small farmers.

At present, more than 1.07 million agricultural socialized service organizations have become intimate "field nannies" of farmers, and their services have driven more than 91 million small farmers, covering more than 1.97 billion mu.

The relevant person in charge of the Ministry of Agriculture and Rural Affairs said: "In the direction of consolidating the modern large-scale agricultural management system, it is necessary to improve and perfect the mechanism of linking agriculture with agriculture. Adhere to the combination of strengthening the driving efficiency and improving the driving ability, scientifically and reasonably determine the driving mode and the degree of benefit, improve and improve the long-term mechanism of’ accurate’,’ stable’ and’ long-term’, and promote the organic connection between small farmers and modern agricultural development. "

A strong country must first strengthen agriculture, and a strong agriculture can strengthen the country. The fundamental way out for agriculture lies in modernization. In the new era and new journey, under the guidance of Socialism with Chinese characteristics Thought, the supreme leader in the new era, hundreds of millions of peasants Qi Xin have worked together to build a better life, agricultural modernization has made great strides forward, and the vast fields have unlimited hopes.