1905 movie network news Hollywood action thriller visual effects giant will officially land in national cinemas on Friday, March 31, and the pre-sale is now in full swing. This latest masterpiece, created by the screenwriter team, will once again present treading on thin ice’s movie-watching experience, and take the audience to the road of escape facing the prehistoric beasts. A few days ago, the film released a clip of "Confronting the Beasts", in which the beasts who dominated the Cretaceous earth entered a state of battle and teamed up to besiege the survivors who were seriously injured. The inescapable plight was worrying.

The film "Escape from Cretaceous" was released for the first time, showing the tragic situation of two survivors "confronting the beasts". Commander Mills (decoration) was accidentally injured while trying to search for the signal. At the same time, several wild animals emerged from the fog and eagerly approached this "prey" that lost its combat effectiveness. With the help of the little girl Kouya (decorated), Mills barely resisted the first attack of the beast at this critical moment. But survival is only the beginning, more beasts show their fangs, and a more violent attack is coming!

Through this clip of "Confronting the Beasts", the audience can appreciate the escape atmosphere of "Escaping from the Cretaceous". Some people commented excitedly: "I feel the horror of the beast riding on the face through the screen." In the movie, Mills and Koya accidentally came to the earth 65 million years ago. In this prehistoric world dominated by wild animals, they had to fight hard to survive. The future vs prehistoric cross-time confrontation is officially staged, get ready, and the big screen will meet the extreme impression of "seeing palms sweating"!

In order to create such an immersive experience, the founders have made a lot of efforts behind the scenes. The director revealed: "Most of the filming of this film is in real locations and real scenes, and we will not stop even in thunderstorm weather." This ingenious shooting method enables the actors to make the most realistic response. The film’s protagonist, Mills, is played by Oscar-nominated actor adam driver. As the hottest powerful actor in recent years, he has contributed to the superb performance of "film emperor" in this film. His expressive body language and distinct emotional changes have brought the audience a "suffocating" experience with rapid heartbeat, and he has also won unanimous praise from film critics: "adam driver once again proved his performance skills and deserves to be the representative of the new generation of Hollywood acting school!"

"Escape from Cretaceous" was directed by Scott Baker, a screenwriter team in Quiet Place, and the director of "Spider-Man" series was the producer, starring adam driver and Ariane greenblatt. On March 31, Japan was released nationwide on Friday, and the pre-sale was in full swing!

Red eye, wide body component. Electric sunroof black sports spoiler 4C navigation system 8.4-screen convenience package (blind spot intersection alarm same color rearview mirror high-intensity discharge headlight) interior package (gray aluminum cut interior Nappa interior seat heating ventilation steering wheel heating suture instrument panel deerskin interior rearview mirror memory power tilting telescopic steering column) SRT package (black label external black badge fender Redeye label SRT grille badge STR spoiler logo) red seat belt.

Dodge Hellcat SRT adopts the latest design concept of Dodge family, and its overall shape is more sporty. The instrument panel adopts the combination design of double instrument panels and LCD screen, and the center console adopts split type with central LCD screen. It has a sporty atmosphere, including a bottom steering wheel, sports seats, carbon fiber-like interior parts and aluminum alloy decorative panels.

The 2023 Dodge Hellcat Wide-body Red-Eye Cat is equipped with a 6.2L V8 supercharged HEMI engine with an output of 808 HP (797 British HP) /960 Nm, which is called the muscle car with the highest horsepower acceleration, the fastest speed and the fastest mass production. 0-96 km accelerates for 3.4 seconds, 0-400 m accelerates for 10.8 seconds, the tail speed is 210 km, and the top speed is 327 km/h. It is also equipped with "ejection preparation" Line Lock mode, which can easily burn tires in situ.

The aggressive front face of 22 Hellcat wide-body red-eyed cat muscle sports cars is the most striking place, like a shark with a big mouth, which is quite powerful. The integrated taillight uses 164 LED light sources, and the tail wing improves its stability at high speed.

22 Dodge Hellcats Wide-body Red-Eye Cats From the front of the car, the two headlights are as sharp as eagle eyes, and the flexible lines of the whole body overflow with an aura. If you like passion, sports cars and speed, this Dodge Challenger wide-body red-eyed cat is the best choice.

The tail wing added above the rear of the wide-body red-eye cat of 23 Dodge Hellcats improves its stability at high speed, while the bottom spoiler and large-caliber double-tail row more thoroughly demonstrate its powerful performance. The lines on the side are more rough and overbearing broken lines, which are very muscular. They are equipped with 20-inch Group 2 alloy wheels and NTOS racing tires, which have excellent grip.

The 23 Dodge Hellcat wide-body red-eyed cats have a sporty atmosphere, including a flat-bottomed steering wheel, a sports seat, carbon fiber-like interior parts and aluminum alloy decorative panels. The embedded round headlights look extremely fierce, revealing the heroic style of American muscle cars.

　　Moscow, August 31st (Xinhua) Reporter Lai Yuhong and correspondent Jing Haihui reported that the cycling race of "International Military Competition -2020" and "Tank Biathlon" ended on August 30th, and all three teams of China team successfully completed the race and advanced to the semi-finals.

　　There are 45 teams from 16 countries and regions participating in the cycling race of "Tank Biathlon". The 702nd team, 703rd team and 701st team from China won the third, fourth and tenth place respectively.

　　On the morning of August 30th, local time, China’s team 703 made its debut at the Russian Alabino shooting range, competing fiercely with Belarusian, Serbian and Azerbaijani teams. During the competition, although the third shot missed the target in the artillery shooting, the members of the 703 car group quickly adjusted their mentality and galloped all the way through obstacles such as wading fields, soil ridges and rutting bridges. The anti-aircraft machine guns and parallel machine guns all hit the target, and finally won the first place in the group and ranked fourth in the cycling race. So far, all three teams of the China team have finished the race and won the first place in the group.

　　"International Military Competition -2020" was held in Russia, Belarus, Armenia, Azerbaijan and Uzbekistan from August 23rd to September 5th. 156 teams from more than 30 countries and regions participated in the competition, with more than 5,000 participants. China has sent six teams and more than 260 officers and men to participate in six events, such as "Top Scout", "Two Tanks", "Safe Environment", "Open Water", "Automobile Expert" and "Airborne Platoon".

　　"Tanks Biathlon" is the highlight of "International Military Competition -2020", which is divided into two stages: cycling race and relay race. The semi-final will start on September 1st, and it will be carried out in the form of relay race. Three teams from the same participating country will use one equipment to relay the driving and shooting tasks.

　　Above: On August 30th, the team from China participated in the cycling race of "Tank Biathlon" at the Russian Arabino shooting range. Xinhua news agency

　　BEIJING, May 27th (Xinhua) The Dragon Boat Festival, also known as the "Zongzi Festival", is of course indispensable for people all over the country to welcome the long-awaited three-day holiday: eating Zongzi! At this time of the year, the dispute over the sweetness and sweetness of zongzi will come back. But in fact, in addition to the traditional salty and sweet taste, there have long been many magical tastes! Which of the following zongzi tastes the most wonderful? Do you have any dishes? Let’s take a look.

　　1. Crayfish dumplings

　　Chinese is really in love with crayfish! Glutinous rice is soft, lobster is fat and delicious, and you can smell spicy and spicy midnight snack through the screen. On the way of crayfish’s 100-year death in China.

　　2. Spicy rice dumplings

　　It sounds full of the feeling of dark cooking. I wonder if it will be really spicy after opening it, which will make your tongue anxious to get angry.

　　3. Wuren Zongzi

　　Say! Are you an undercover agent sent by Wuren Moon Cake? ! This annual Mid-Autumn Festival makes people feel frightened, and finally extends its claws to Zongzi. Just seeing this combination is enough to remember the fear of being dominated by Wuren moon cakes in those years … …

　　In addition to these wonderful zongzi that have already appeared, I heard that there is a new kind of zongzi with magical taste about to be born this Dragon Boat Festival, that is — — Wahaha haha zongzi. Wahaha, a "cross-border maniac" from the beverage industry, is said to be a perfect replica from sour and sweet AD calcium milk to fragrant and glutinous eight-treasure porridge, from cool and exciting iced black tea to the new ice cream matcha just listed this year.

　　It is understood that Wahaha’s official Weibo began to collect the taste of zongzi that netizens want in early May. Although the scope is limited to Wahaha products, … … My friend, that’s Wahaha, an all-round player covering all categories, from drinks to canned food, from pure yogurt juice to coffee and cola eight-treasure porridge! Netizens’ brains are wide open. Apart from the routine operation of "AD calcium milk flavor", there are also "Gowasu flavor", "beer tea refreshing flavor" and even "pure water flavor", and various magical flavors emerge one after another. Fortunately, in the voting stage, everyone came to their senses and voted for four tastes that sounded fun and delicious, namely, AD calcium milk, eight-treasure porridge, iced black tea and ice cream matcha, which together formed the most anticipated novel zongzi NO.1 this summer!

　　Old-fashioned domestic products are innovating again, and they are playing more and more on the road of cross-border

　　After Wahaha officially announced that it would launch "Haha Zongzi" in a limited time, netizens expressed their desire for mass production and worried that their hand speed was too slow, and they missed the AD calcium milk moon cake like last year.

　　Wahaha, a "cross-border maniac", launched a limited-edition AD calcium milk moon cake as early as the Mid-Autumn Festival last year, and launched a set of limited-edition nutrition express makeup plates during Christmas, which was warmly sought after by young consumers.

　　It is reported that the AD calcium-milk-flavored moon cakes were robbed in less than one second, and the Nutrition Express Makeup Plate was recommended by bloggers from Weibo, bilibili, Xiaohongshu and other social platforms. Up to now, some netizens still ask where they can buy them.

　　What is more important for the brand is that more and more consumers have realized that Wahaha is obviously different. TA is no longer just the childhood favorite who lives in memories. Wahaha has become fun and young enough to mingle with the young people now.

　　According to the official sales information, the "Wahaha Haha Zongzi" launched this time will be officially launched at 10:00 on May 30th and 10:00 on June 3rd on the WeChat "Habao Amusement Park" in WeChat official account, which is officially operated by Wahaha, and it’s a spike in 0 yuan, just pay the postage.

　　[Aika Auto Vision Original]

　　Children’s Day is coming, how can you let your children feel your deep love? I think that "you ask me how much I love you, and toys represent my heart", and only toys are the most conquering. But what kind of toys should I choose? Parents have no choice but to fall into the dilemma of "it is difficult to choose gifts and it is difficult to go to heaven". Think about our childhood, transformers, four-wheel drive racing cars and other toys, all left us with simple and beautiful childhood memories. But that era has long passed, and for the rich people now, they just like to play with some ordinary objects to make them luxurious and fancy. Today, let’s take a look at the toy cars of those "trenches", which can definitely kill everything in your childhood. Don’t believe it.

　　The electric children’s car must be familiar to everyone. At the beginning, it was mainly designed for children. In order to adapt to children’s behavioral ability, prams are generally simple in structure and easy to operate. Even adults can drive remotely outside the car, and the speed will not exceed 5 km/h. But the toy car we want to talk about today is completely different from the ordinary children’s toy car that can be seen everywhere on the street. They are made in strict accordance with the real car model, and even the roof, windshield, headlights and decorative parts have been copied intact, which is actually a mini car. Of course, the price is by no means affordable for ordinary families.

Ferrari children’s car

Mclaren P1 children’s car

Nicholas Mee DB5

Rolls-royce SRH

　 　 　 Different from the children’s version of electric cars that cost thousands of dollars in the market, the current "baby carriage" has more scientific and technological content and is closer to the appearance of real cars in real life. Although it is much smaller than an ordinary car in size, it is by no means much cheaper than a car in price. With the popularization of automobile culture in China and the improvement of income level, wealthy people in China have also turned their attention to these advanced toy cars, and some domestic enterprises have begun to set foot in this field.

Ruby Lin

According to Taiwan media reports on the 26th, Ruby Lin, 46, married Wallace Huo in 2016, and had a daughter "Little Dolphin". From time to time, she shared her parenting life on social platforms. Ruby Lin was found to have had her hair cut short when she attended an endorsement event on 26th. She revealed that her daughter was crying over this, and asked Ruby Lin to grow it as soon as possible. She also revealed that Wallace Huo spoiled her daughter and even asked her to wear nail polish and eye shadow.

Ruby Lin’s 5-and-a-half-year-old daughter loves to braid her hair. After she cut her hair short, her daughter cried and said, "Mom, you cut your hair!" Ruby Lin is required to keep her hair long. Usually, she is required to wear a skirt at home, which makes Ruby Lin laugh and cry. When she has special needs, she will go to her father Wallace Huo: "Because I have more regulations, I usually skip me to find my father, because my father is reluctant to refuse."

Wallace Huo even accepted her daughter’s request for makeup. Ruby Lin said with a smile: "I was bored by her (daughter) and told her to go to her father, who didn’t wear makeup." My daughter painted everything from nail polish to eye shadow, and all of them used super bright colors. Ruby Lin couldn’t help taking pictures to commemorate her.

　　Xinhua News Agency, Beijing, May 28th Title: Well-known enterprises "fall down when they say it", and virtual cards become new "slots" — — Re-investigation of prepaid card consumption chaos

　　Xinhua News Agency reporter Yang Yang

　　"Beauty, what about swimming and fitness?" I believe many people have heard of similar "strike up a conversation". Merchants use various discounts to attract you to spend money on cards, but once you pay for it, you may fall into a ring-by-ring routine … …

　　According to the reporter’s investigation, as an emerging business model, prepaid card consumption is favored by many businesses because of its convenience and benefits. However, the deep-seated reasons, such as the blind spot in the prepaid card filing system, light punishment and imperfect credit information system, have led to frequent chaos and repeated prohibitions in this field, and some well-known enterprises are also involved.

　　Well-known enterprises "say it, but they will fall", but they are still applying for new cards when they can’t pay.

　　"If you come to apply for a card today, you can enjoy the lowest price, buy it for two years and get it for one year!" In March this year, Mr. Gao spent 2,700 yuan on a three-year fitness card in Beijing Haosha Fitness Jinsong Store.

　　However, after the May 1 ST, this well-known chain gym has had problems such as the cancellation of group exercises, the closure of swimming pools, the disconnection of power and hot water, and the failure of equipment without maintenance. "Seven out of 10 treadmills are broken, and the front desk still shows ‘ Direct entry without swiping the card ’ Brand. " A member told reporters.

　　Even so, the gym is still selling cards. According to members’ memories, on May 6th, Xiaoli, a salesman, was still soliciting guests in a circle of friends. Later, according to another salesperson, in March this year alone, the store’s sales reached more than 500,000 yuan.

　　The gym can’t be used normally, and many members have proposed to return their cards. However, Mr. Gao found that the contract said, "This is a special card, and it can’t be returned." After rummaging through his pockets, he realized that he didn’t even give the payment receipt and invoice. Mr. Shan, the operation manager of the gym, said: "The company has no money and can’t refund the fee."

　　According to the national enterprise credit information publicity system, "Beijing Haosha Jianli Fitness Service Co., Ltd." on the official seal of the membership card agreement was listed in the business exception list of the industrial and commercial departments on April 30 this year, and its shareholder Haosha Ai Ya (Beijing) Fitness Service Co., Ltd. was also listed in the business exception list on March 20. The reporter called the company’s reserved phone number several times, but never contacted the senior person in charge.

　　Relevant sales staff of Haosha Jinsong Store revealed that due to the break of the company’s capital chain, some stores in Beijing will be closed.

　　The relevant person in charge of Shuangjing Industrial and Commercial Office of Chaoyang Branch of Beijing Administration for Industry and Commerce told the reporter that the industrial and commercial department is negotiating with Haosha Fitness to solve related problems. Haosha Jinsong Store will be taken over by other companies, but this company can only provide services and cannot handle the refund problem. If you really need a refund, it is recommended to go to court as soon as possible.

　　Small enterprises are the hardest hit areas for complaints, and virtual cards become new "slots"

　　The "Analysis of Complaints Accepted by National Consumers Association in 2018" released by China Consumers Association shows that life and social services rank first in service complaints. In the field of service segmentation, remote shopping, beauty salons, catering, maintenance and repair, and fitness services are all on the list.

　　By combing typical cases in various places, the reporter found that prepaid card consumption disputes are mainly concentrated in the service industry, especially in the fields of beauty salons, fitness, photography, car beauty, catering, etc. Among them, some small-scale enterprises have become the hardest hit areas for running away and disputes.

　　"The money in the prepaid card is the money that consumers deposit in the other party’s account in advance to fulfill multiple contracts. It should be consumed once, and the operator deducts money from the card once. " Heshan, president of china law society Consumer Rights Protection Law Research Association, said.

　　"But in real life, prepaid transactions are gradually deviating from the original intention, becoming a means for illegal operators to infringe on the legitimate rights and interests of consumers, resulting in a large number of legal disputes." Wang Jijin, supervisor of Beijing Lawyers Association and lawyer of Construction Law Firm, said.

　　In addition, the reporter’s investigation found that with the development of mobile Internet, online prepaid consumption has gradually become a new complaint "slot". Recently, a number of consumers told reporters that they had booked flowers for several months in their lives, but they found that the applet was offline after not receiving it several times.

　　Liu Junhai, a professor at the Law School of Renmin University of China, said that the low cost of corporate dishonesty and the high cost of consumer rights protection led to a significant increase in prepaid arbitrage.

　　Education, fitness and other industries are not included in the record, and combination boxing is needed to control the chaos.

　　In response to the frequent chaos of prepaid cards in various places, as early as September 2012, the Ministry of Commerce issued the Measures for the Administration of Single-use Commercial Prepaid Cards (Trial), requiring card-issuing enterprises to go to the competent commercial authorities at all levels for filing within 30 days from the date of launching the single-use card business, and implement a fund depository system for related enterprises, and deposit funds in commercial banks according to a certain proportion of the funds received in advance. Once the violation occurs, it can form a constraint on enterprises.

　　"But the reality is that there is a lack of supervision over the subsequent use of depository funds. In addition, the measures only involve ‘ Retail, accommodation and catering, residential service ’ Three industries, but there is no coverage for high-incidence areas such as fitness, beauty salons, education, entertainment, online car, and individual industrial and commercial households. " Wang Jijin said that in addition, a fine of less than 30,000 yuan will be imposed on the illegal acts of card issuing enterprises or card selling enterprises, which is relatively light and difficult to play a deterrent role.

　　Heshan suggested raising the threshold for issuing prepaid cards for a large number of individual industrial and commercial households, for example, stipulating that operators should pay a deposit or provide corresponding guarantees in order to obtain the right to issue cards.

　　Qiu Baochang, an expert from the Expert Committee of China Consumers Association, suggested setting a qualification threshold for card-issuing merchants and their main managers, such as requiring operators to have no major violations of laws and regulations and no bad records of fraudulent consumer behavior. Wang Jijin suggested: "Establish a blacklist system as soon as possible, register and publicize untrustworthy enterprises and individuals, and raise the threshold in handling industrial and commercial licenses."

　　Some insiders also believe that the mode of prepayment leads to the one-way risk of consumers, and this consumption mode can be abandoned. Commercial enterprises should rely on improving services instead of paying in advance and then discounting to tie consumers down.

As an important protection in the process of drug development, patent is self-evident. The number of patents owned by an enterprise not only forms important intellectual property protection for products, but also reflects the status and value of the enterprise. However, patents are also divided into "three, six and nine grades". A high-quality authorized patent not only protects the value of the product, but also has high value itself. However, a patent full of loopholes is difficult to obtain authorization. Even if it is authorized, it will be easily challenged by competitors, and eventually it will be "invalid", which will bring serious economic losses to enterprises. Therefore, it is extremely important for the pharmaceutical industry to understand "invalid patent" and achieve "from defense to attack"

What is the "patent invalidation system"

Patent invalidation system, which is regarded as "a corrective procedure for wrong patent authorization", has attracted much attention in patent systems in various countries, and its essence has the functions of error correction, defense and defense. The invalidation of patent will have a direct impact on the validity of patent right, and whether the patent right is effective and stable is an important premise and index to measure the quality of patent. Generally speaking, the invalidation of an invention-creation experience is finally kept valid, and its patent value is higher, which will also have an important impact on the subsequent measures taken by the patentee and the invalid claimant.

With the rapid increase in the number of drug patent applications and patent authorizations in China, there are more and more phenomena of using invalidation to challenge other people’s drug patents and expand their own benefits. Even the patent departments of some companies will organize personnel to "attack" competitors’ patents; At the same time, in order to keep the core claims of their own patents, some patentees have reduced their patent protection scope through invalidation to avoid subsequent patent litigation. In short, it is one of the necessary skills for every pharmaceutical company to protect its "core rights" by using the patent invalidation system as much as possible.

Based on the case of sildenafil patent in Pfizer, the author explains the importance of "invalid patent". In this case, the key points of the game for "invalid reasons" are as follows:

1. The patent specification shall explain the drug activity, preparation method, effective dosage and use method of the drug, and describe the medical effect of the drug on the second indication in detail through animal experiment or clinical trial data. However, the writing of the instructions is far from the above requirements, so that technicians in the technical field can’t know what medicine to use, what disease to treat, how to use the medicine correctly and how effective it is by reading the instructions without creative labor.

Second, this patent specification only generally records that the compounds of the present invention have been tested in vitro and found to be strong selective inhibitors of PDE-V with specificity for cGMP; Ordinary technicians in this profession can’t see what the so-called particularly preferred compounds are from this description, while the claims seek to protect the use of four products, and ordinary technicians in this profession can’t determine the relationship between these four products and the particularly preferred compounds in the above text description.

Three, the applicant made a major amendment to the claim, in fact, after the original claim was deleted and reassembled. This modification cannot be directly and undoubtedly derived from the information disclosed in the original specification and claims. Obviously, because the original specification and the claims did not fully disclose that the products in the present claims have clear medical functions and unexpected technical effects as required by the Patent Law, the modification results of the claims cannot be directly and undoubtedly derived from the specification and the original claims.

4. As the existing cGMP and PDE inhibitors can be used to treat ED, it has been suggested and suggested many times in the relevant literature, it is not difficult for ordinary technicians in this field to draw the results in the claims from these tips and suggestions.

On the above questions, Pfizer answered each "invalid reason" one by one, proving that there is no problem with the creativity of its patent. After that, the original Patent Reexamination Board of China National Intellectual Property Administration finally declared the patent authorized by the original research company Pfizer invalid through in-depth research. Pfizer was dissatisfied with the above decision of the original re-examination board, and immediately appealed to the Beijing No.1 Intermediate People’s Court to sue the original patent re-examination board, requesting the court to cancel its decision of invalidation. After repeated debates, in 2006, the Beijing No.1 Intermediate People’s Court officially announced the revocation of the decision of No.6228 made by the original Patent Reexamination Board. Since then, Pfizer’s Viagra has made huge profits in China every year, but sildenafil produced by domestic generic drug companies cannot be listed. This situation continued until the listing of domestic sildenafil "Jinge" in 2014.

The importance of "public opinion"

The application for "invalid patent" can not be disputed only after authorization. When the application documents appear, they can be questioned in the form of "public opinions". Article 48 of the Detailed Rules for the Implementation of the Patent Law stipulates that "from the date of publication of an application for a patent for invention to the date of announcement of the grant of a patent right, anyone may put forward opinions to the patent administration department of the State Council and explain the reasons", which is also called "public opinions" in the industry. Pharmaceutical enterprises should make full use of this provision to protect their own interests to the maximum extent.

The rosiglitazone case illustrates the importance of "public opinion". In 1993, GlaxoSmithKline applied for a series of patents including pharmaceutical compounds and compositions, such as the invention patent application with the application number of CN98805686.0, which requested to protect the pharmaceutical composition containing 2mg~8mg of rosiglitazone. The application date was June 2, 1998, the publication date was July 5, 2000, and it was authorized on July 2, 2003. It can be seen that it took about three years from the disclosure of the patent application to the announcement of authorization. During these three years, the relevant enterprises in China did not put forward any "public opinions".

In 2004, when Shanghai Sanwei Pharmaceutical, Zhejiang Wanma Pharmaceutical, Chongqing Taiji Group and other domestic enterprises have invested a lot in research and development of this drug or entered the stage of drug registration, they suddenly received a lawyer’s letter from GlaxoSmithKline, claiming that the products developed by the above-mentioned enterprises infringed their patent ZL98805686.0, demanding that the above-mentioned enterprises stop the research and development and listing of related products and compensate for the losses. As a result, these enterprises jointly requested the original patent reexamination board to declare the patent invalid. Although the case ended in GlaxoSmithKline’s abandonment of the patent, it lasted for a long time and had a great impact, causing huge losses to China enterprises.

Analyzing the case, when domestic pharmaceutical companies were ready for production and even obtained the approval of drug production, they found that they were facing the infringement lawsuit of foreign pharmaceutical companies, so they passively responded and rushed to the original Patent Reexamination Board to file a patent invalidation request in an attempt to invalidate the patent. In this case, even if the patent right can finally be declared null and void in whole or in part, China enterprises still face huge market risks and interest losses due to the long trial period and long-term uncertainty of rights.

In fact, an application for a patent for invention will be published within 18 months from the date of filing (unless the applicant requests it to be published in advance), and then the Patent Office will start substantive examination on it at the request of the applicant. If the examiner thinks that the patent application conforms to the relevant provisions of the Patent Law and the Detailed Rules for the Implementation of the Patent Law, the patent right will be granted and announced to the public, otherwise, it will be rejected. After the patent is granted, anyone (the third party) who thinks there is a problem with the patent grant may go to the relevant department to request that the patent be declared invalid. Of course, if you are not satisfied with the invalidation or review decision made by the relevant department, either party can also bring a lawsuit in court. Generally speaking, after an invention patent is published 18 months from the date of filing, it sometimes takes 2-4 years to decide whether to authorize it. At this stage, whether the patent application can be finally authorized is still in a pending state, which is the time allowed to put forward "public opinions" as stipulated in Article 48 of the Detailed Rules for the Implementation of the Patent Law. It can be seen that how to reduce the losses caused by patent disputes relatively, the "public opinion" before patent authorization is very important.

In recent years, Chinese pharmaceutical enterprises have paid more and more attention to the protection of intellectual property rights. The intellectual property departments of many large pharmaceutical companies have even reached the scale of 100 people. In addition, for some important patent applications, some pharmaceutical companies will take them to more professional patent agencies for secondary processing and polishing before submitting applications. It can be seen that pharmaceutical companies pay more and more attention to patent application and are more and more cautious about controlling patent quality. With the increasing number of patent challenges and invalid patent applications, the trend of domestic pharmaceutical companies turning from defending to attacking intellectual property rights has been initially established.

(Qiang Sen)

An ecological farm built on the river bank, in the form of quadrangle dwellings, has green grass in the yard, and a sewage pipe is connected from the kitchen behind the yard to the river. Reporter Bai Tiantian photo

　　Imagine a family driving to an ecological farm far away from the city on a weekend, experiencing country life and tasting delicious farmhouse food. How do you feel when we leave comfortably, but leave behind the black and smelly wastewater that is directly discharged into farmland and rivers?

　　Nowadays, all kinds of farmhouses and ecological farms are blooming everywhere, becoming the hot spots of rural tourism. Half-monthly reporters have recently conducted field investigations in many places and found that many farmhouses have outstanding problems of "front door ecology and back door sewage discharge", and pollution prevention and supervision are lagging behind. Some farms that flaunt "ecology" are not worthy of the name, and the sewage discharge place has become a stinking ditch, and the lampblack discharge place has become a "black land".

　　Ecological farms are not necessarily "ecological", and waste water and oil are discharged at will.

　　Pastoral scenery, green ecology, native dishes … … This is a "propaganda language" played by many farmhouses and farms. Recently, a semi-monthly reporter walked into an ecological farm built on a river bank in a county in Dongting Lake area. The farm is a courtyard house with more than 10 boxes, green grass in the yard, cool breeze on the terrace near the river and pleasant environment. Walking through the yard to the back of the kitchen, you can see a 4-meter-long, covered with blue colored steel tiles, and some hidden pipes lead directly into the river. The water flowing out of the pipe is obviously dirty.

On a farm around a county town, kitchen sewage and waste were discharged into a small pond for a long time, filled with black or yellow wet and sticky dirt, next to a rice field and an irrigation canal. Reporter Bai Tiantian photo

　　In this regard, the farm staff disapprovingly said: "The sewage in the kitchen is discharged like this, and it is washed away as soon as it rises."

　　A farm close to a county town, the scene of sewage discharge is even more shocking. When the reporter asked the farm owner for half a month, how to discharge the sewage? The female boss’s answer is: "We discharged into the sewer." But when the reporter went to the back of the kitchen, a bad smell came head-on, and I saw a small pond next to it, full of black or yellow wet and sticky dirt. On one side of the pond, there are paddy fields and an irrigation canal — — It turns out that this is the so-called "sewer".

　　In another mountainous town, the annual spring flower viewing season is the tourist peak season, and tourists come here in an endless stream. A farmhouse named "Central Local Restaurant" has a reception capacity of more than 20 tables. Half a month, the reporter saw that the oil pollution, dishwashing water and toilet sewage of this farmhouse lampblack machine all merged into the next canal. The farmhouse is surrounded by farmland, and the early rice is growing green. These blackened wastewater turns into irrigation water and flows into the fields.

　　Similar pollution phenomenon is not a case. A person in charge of the environmental protection department said frankly that in the current rural environmental pollution, the wastewater, exhaust gas, lampblack and solid waste from farmhouses and farms are important sources of pollution. "Many farms are directly discharging pollutants in order to maximize their interests."

A farmhouse that focuses on "local dishes", the kitchen waste water is directly discharged into the canal behind the house, forming a black greasy dirt for many years. Reporter Bai Tiantian photo

　　Shuguang Environmental Protection is a non-governmental environmental protection public welfare organization in Hunan. This year, they launched a survey on the water pollution in farmhouses. Tan Yongchao, director of water project, said that at present, his team members have visited more than 20 farmhouses on the spot and found that toilet sewage is generally treated by septic tanks, while most kitchen wastewater is "directly discharged".

　　In April, Shuguang Environmental Protection conducted a sampling inspection of wastewater samples from the outlet of an ecological farm around Changsha. The test items included suspended solids, chemical oxygen demand, total phosphorus, total nitrogen and ammonia nitrogen. According to the test report, if compared with the pollutant discharge standards of urban sewage treatment plants, many indicators of the samples seriously exceed the standard. For example, the chemical oxygen demand (COD) is 373 mg/L, which is more than seven times that of Grade A standard and three times that of Grade III standard.

　　"I pollute but I don’t control it", and environmental protection can only rely on "awareness"?

　　During the tourist season or weekends and holidays, some farmhouses and ecological farms are bursting with popularity, and operators earn a lot of money. But when it comes to environmental protection, they often "have nothing to do with themselves and hang high", and the prevention and control of pollution can only rely on "awareness".

　　In the interview, farmhouse operators generally showed two typical mentalities. One mentality is that "the law does not blame the public." An eco-farm owner pointed to the pipeline leading directly to the village canal and said without hesitation: "Sewage is directly discharged into the canal without treatment. In rural areas, everyone does this and it has no impact."

　　One mentality is "I pollute and the government pays". After a half-month talk, reporters asked a number of operators and found that they generally lacked the concept of "who pollutes, who governs", and thought that pollution control is a matter for the government. The owner of the farm near the county said that it would cost thousands of dollars to remove waste water and waste oil once, which was not cost-effective, and should be paid by the government. Before the village dredged the canal, she didn’t clean the sewage pond of her farm by the way, and she still complained about it.

In a village famous for enjoying flowers in spring, the oil pollution, dishwashing water and toilet sewage of a farmhouse lampblack machine in rice fields are "three in one", and the blackened wastewater is directly discharged into the irrigation canal. Reporter Bai Tiantian photo

　　On the other hand, some places lack restraint and supervision on the pollution of farmhouse music. A person in charge of the local environmental protection bureau said that in the past, rural environmental improvement focused on "visible garbage" and carried out cleaning projects for villages, schools and roads, but not enough attention was paid to the "root cause" of air, water and soil pollution. According to the regulations, environmental impact assessment should be carried out in the construction of ecological farms, but the local area is basically blank.

　　In 2017, the Environmental Protection Bureau of Linyi County, Hunan Province investigated an ecological farm project and found that it was built without going through the EIA approval procedures, put into operation without supporting pollution control facilities, and made administrative penalties. However, similar cases are rare. Most of the farm operators interviewed by reporters in half a month said that they did not conduct environmental assessment, and the inspection of environmental sanitation rarely involved smoke exhaust, drainage and exhaust.

　　Relatively speaking, star farms have done a good job in environmental protection. In a five-star farm with an area of more than 80 mu and an investment of tens of millions, facilities such as sewage purification tanks and fume purifiers are readily available, designed and installed by professional environmental protection companies. The owner of the farm said that the star rating has clear environmental protection requirements, so they conducted an environmental assessment and built pollution control facilities.

A five-star farm has done a good job in environmental protection, and built facilities such as sewage purification pond and lampblack purifier. Reporter Bai Tiantian photo

　　Farmhouse "blooms more", and environmental protection should also "keep up step by step"

　　With the rise of rural tourism and global tourism, farmhouses and ecological farms are showing the trend of "multi-point flowering". The reporter learned from the semi-monthly talk that in recent years, in key areas such as urban suburbs, reservoir wetlands and scenic spots, farmhouse music is gradually being brought into the scope of supervision and rectification, and environmental pollution problems have begun to spread to some remote counties and townships and emerging rural tourist spots.

　　Liu Shuai, director of the Supervision Department of the Environmental Protection Committee of Hunan Provincial People’s Congress, said that at present, pollution prevention and control of farmhouse music is well done in developed areas such as the Yangtze River Delta and around big cities, but it is still weak in many other places, which should be further paid attention to and strengthened management.

　　Liu Shuai believes that it is necessary to explore rural pollution control modes according to local conditions, such as building "upgraded versions" of constructed wetlands and septic tanks in villages with scattered populations. In the construction and operation of farmhouse music, the environmental impact assessment system should be implemented at the front end, and the departments of agriculture and tourism should be combined at the end to strengthen environmental law enforcement.

　　Wang Gaoliang, deputy director of the Environmental Protection Bureau of Hengyang County, said that this year, the local environmental protection department will focus on rural environmental improvement, requiring farmhouses to standardize the installation of lampblack and sewage treatment facilities, and promote the construction of four sewage purification ponds and "constructed wetlands+oxidation ponds" suitable for rural areas. The basic requirement is that they cannot be discharged directly. If the farmhouse fails to meet the environmental protection requirements, a rectification letter will be issued and penalties will be imposed.

　　Liu Hongli, Director-General of Shuguang Environmental Protection, suggested that the principle of "whoever pollutes should treat" should be adhered to for farmhouses and ecological farms. At the same time, the government can also introduce guiding measures, like remediation of aquaculture pollution, and give certain subsidies to the construction of pollution control facilities according to the scale of farmhouses, starting with newly-built farmhouses and star-rated farms, and then gradually solving the problem of stock pollution. (Talk to reporter Bai Tiantian for half a month)

　　New pollutants endanger the ecological environment and human health, which is one of the global environmental problems. The CPC Central Committee and the State Council attached great importance to the treatment of new pollutants. Recently, the General Office of the State Council issued the Action Plan for the Treatment of New Pollutants (Guo Ban Fa [2022] No.15, referred to as the Action Plan), which pointed out the direction for the treatment of new pollutants in the future. The Action Plan embodies China’s idea of actively participating in global environmental governance, which is of great significance for building a beautiful China and building a community of life on earth.