Ruby Lin Rare Show Happiness Daily Sharing Wallace Huo’s Pet Daughter Behavior

Ruby Lin

Ruby Lin

According to Taiwan media reports on the 26th, Ruby Lin, 46, married Wallace Huo in 2016, and had a daughter "Little Dolphin". From time to time, she shared her parenting life on social platforms. Ruby Lin was found to have had her hair cut short when she attended an endorsement event on 26th. She revealed that her daughter was crying over this, and asked Ruby Lin to grow it as soon as possible. She also revealed that Wallace Huo spoiled her daughter and even asked her to wear nail polish and eye shadow.

Ruby Lin’s 5-and-a-half-year-old daughter loves to braid her hair. After she cut her hair short, her daughter cried and said, "Mom, you cut your hair!" Ruby Lin is required to keep her hair long. Usually, she is required to wear a skirt at home, which makes Ruby Lin laugh and cry. When she has special needs, she will go to her father Wallace Huo: "Because I have more regulations, I usually skip me to find my father, because my father is reluctant to refuse."

Wallace Huo even accepted her daughter’s request for makeup. Ruby Lin said with a smile: "I was bored by her (daughter) and told her to go to her father, who didn’t wear makeup." My daughter painted everything from nail polish to eye shadow, and all of them used super bright colors. Ruby Lin couldn’t help taking pictures to commemorate her.

Re-investigation on the chaos of prepaid card consumption: well-known enterprises "say it and fall"

  Xinhua News Agency, Beijing, May 28th Title: Well-known enterprises "fall down when they say it", and virtual cards become new "slots" — — Re-investigation of prepaid card consumption chaos

  Xinhua News Agency reporter Yang Yang

  "Beauty, what about swimming and fitness?" I believe many people have heard of similar "strike up a conversation". Merchants use various discounts to attract you to spend money on cards, but once you pay for it, you may fall into a ring-by-ring routine … …

  According to the reporter’s investigation, as an emerging business model, prepaid card consumption is favored by many businesses because of its convenience and benefits. However, the deep-seated reasons, such as the blind spot in the prepaid card filing system, light punishment and imperfect credit information system, have led to frequent chaos and repeated prohibitions in this field, and some well-known enterprises are also involved.

  Well-known enterprises "say it, but they will fall", but they are still applying for new cards when they can’t pay.

  "If you come to apply for a card today, you can enjoy the lowest price, buy it for two years and get it for one year!" In March this year, Mr. Gao spent 2,700 yuan on a three-year fitness card in Beijing Haosha Fitness Jinsong Store.

  However, after the May 1 ST, this well-known chain gym has had problems such as the cancellation of group exercises, the closure of swimming pools, the disconnection of power and hot water, and the failure of equipment without maintenance. "Seven out of 10 treadmills are broken, and the front desk still shows ‘ Direct entry without swiping the card ’ Brand. " A member told reporters.

  Even so, the gym is still selling cards. According to members’ memories, on May 6th, Xiaoli, a salesman, was still soliciting guests in a circle of friends. Later, according to another salesperson, in March this year alone, the store’s sales reached more than 500,000 yuan.

  The gym can’t be used normally, and many members have proposed to return their cards. However, Mr. Gao found that the contract said, "This is a special card, and it can’t be returned." After rummaging through his pockets, he realized that he didn’t even give the payment receipt and invoice. Mr. Shan, the operation manager of the gym, said: "The company has no money and can’t refund the fee."

  According to the national enterprise credit information publicity system, "Beijing Haosha Jianli Fitness Service Co., Ltd." on the official seal of the membership card agreement was listed in the business exception list of the industrial and commercial departments on April 30 this year, and its shareholder Haosha Ai Ya (Beijing) Fitness Service Co., Ltd. was also listed in the business exception list on March 20. The reporter called the company’s reserved phone number several times, but never contacted the senior person in charge.

  Relevant sales staff of Haosha Jinsong Store revealed that due to the break of the company’s capital chain, some stores in Beijing will be closed.

  The relevant person in charge of Shuangjing Industrial and Commercial Office of Chaoyang Branch of Beijing Administration for Industry and Commerce told the reporter that the industrial and commercial department is negotiating with Haosha Fitness to solve related problems. Haosha Jinsong Store will be taken over by other companies, but this company can only provide services and cannot handle the refund problem. If you really need a refund, it is recommended to go to court as soon as possible.

  Small enterprises are the hardest hit areas for complaints, and virtual cards become new "slots"

  The "Analysis of Complaints Accepted by National Consumers Association in 2018" released by China Consumers Association shows that life and social services rank first in service complaints. In the field of service segmentation, remote shopping, beauty salons, catering, maintenance and repair, and fitness services are all on the list.

  By combing typical cases in various places, the reporter found that prepaid card consumption disputes are mainly concentrated in the service industry, especially in the fields of beauty salons, fitness, photography, car beauty, catering, etc. Among them, some small-scale enterprises have become the hardest hit areas for running away and disputes.

  "The money in the prepaid card is the money that consumers deposit in the other party’s account in advance to fulfill multiple contracts. It should be consumed once, and the operator deducts money from the card once. " Heshan, president of china law society Consumer Rights Protection Law Research Association, said.

  "But in real life, prepaid transactions are gradually deviating from the original intention, becoming a means for illegal operators to infringe on the legitimate rights and interests of consumers, resulting in a large number of legal disputes." Wang Jijin, supervisor of Beijing Lawyers Association and lawyer of Construction Law Firm, said.

  In addition, the reporter’s investigation found that with the development of mobile Internet, online prepaid consumption has gradually become a new complaint "slot". Recently, a number of consumers told reporters that they had booked flowers for several months in their lives, but they found that the applet was offline after not receiving it several times.

  Liu Junhai, a professor at the Law School of Renmin University of China, said that the low cost of corporate dishonesty and the high cost of consumer rights protection led to a significant increase in prepaid arbitrage.

  Education, fitness and other industries are not included in the record, and combination boxing is needed to control the chaos.

  In response to the frequent chaos of prepaid cards in various places, as early as September 2012, the Ministry of Commerce issued the Measures for the Administration of Single-use Commercial Prepaid Cards (Trial), requiring card-issuing enterprises to go to the competent commercial authorities at all levels for filing within 30 days from the date of launching the single-use card business, and implement a fund depository system for related enterprises, and deposit funds in commercial banks according to a certain proportion of the funds received in advance. Once the violation occurs, it can form a constraint on enterprises.

  "But the reality is that there is a lack of supervision over the subsequent use of depository funds. In addition, the measures only involve ‘ Retail, accommodation and catering, residential service ’ Three industries, but there is no coverage for high-incidence areas such as fitness, beauty salons, education, entertainment, online car, and individual industrial and commercial households. " Wang Jijin said that in addition, a fine of less than 30,000 yuan will be imposed on the illegal acts of card issuing enterprises or card selling enterprises, which is relatively light and difficult to play a deterrent role.

  Heshan suggested raising the threshold for issuing prepaid cards for a large number of individual industrial and commercial households, for example, stipulating that operators should pay a deposit or provide corresponding guarantees in order to obtain the right to issue cards.

  Qiu Baochang, an expert from the Expert Committee of China Consumers Association, suggested setting a qualification threshold for card-issuing merchants and their main managers, such as requiring operators to have no major violations of laws and regulations and no bad records of fraudulent consumer behavior. Wang Jijin suggested: "Establish a blacklist system as soon as possible, register and publicize untrustworthy enterprises and individuals, and raise the threshold in handling industrial and commercial licenses."

  Some insiders also believe that the mode of prepayment leads to the one-way risk of consumers, and this consumption mode can be abandoned. Commercial enterprises should rely on improving services instead of paying in advance and then discounting to tie consumers down.

On "Patent Invalidation" of Drug Patents

As an important protection in the process of drug development, patent is self-evident. The number of patents owned by an enterprise not only forms important intellectual property protection for products, but also reflects the status and value of the enterprise. However, patents are also divided into "three, six and nine grades". A high-quality authorized patent not only protects the value of the product, but also has high value itself. However, a patent full of loopholes is difficult to obtain authorization. Even if it is authorized, it will be easily challenged by competitors, and eventually it will be "invalid", which will bring serious economic losses to enterprises. Therefore, it is extremely important for the pharmaceutical industry to understand "invalid patent" and achieve "from defense to attack"

What is the "patent invalidation system"

Patent invalidation system, which is regarded as "a corrective procedure for wrong patent authorization", has attracted much attention in patent systems in various countries, and its essence has the functions of error correction, defense and defense. The invalidation of patent will have a direct impact on the validity of patent right, and whether the patent right is effective and stable is an important premise and index to measure the quality of patent. Generally speaking, the invalidation of an invention-creation experience is finally kept valid, and its patent value is higher, which will also have an important impact on the subsequent measures taken by the patentee and the invalid claimant.

With the rapid increase in the number of drug patent applications and patent authorizations in China, there are more and more phenomena of using invalidation to challenge other people’s drug patents and expand their own benefits. Even the patent departments of some companies will organize personnel to "attack" competitors’ patents; At the same time, in order to keep the core claims of their own patents, some patentees have reduced their patent protection scope through invalidation to avoid subsequent patent litigation. In short, it is one of the necessary skills for every pharmaceutical company to protect its "core rights" by using the patent invalidation system as much as possible.

Based on the case of sildenafil patent in Pfizer, the author explains the importance of "invalid patent". In this case, the key points of the game for "invalid reasons" are as follows:

1. The patent specification shall explain the drug activity, preparation method, effective dosage and use method of the drug, and describe the medical effect of the drug on the second indication in detail through animal experiment or clinical trial data. However, the writing of the instructions is far from the above requirements, so that technicians in the technical field can’t know what medicine to use, what disease to treat, how to use the medicine correctly and how effective it is by reading the instructions without creative labor.

Second, this patent specification only generally records that the compounds of the present invention have been tested in vitro and found to be strong selective inhibitors of PDE-V with specificity for cGMP; Ordinary technicians in this profession can’t see what the so-called particularly preferred compounds are from this description, while the claims seek to protect the use of four products, and ordinary technicians in this profession can’t determine the relationship between these four products and the particularly preferred compounds in the above text description.

Three, the applicant made a major amendment to the claim, in fact, after the original claim was deleted and reassembled. This modification cannot be directly and undoubtedly derived from the information disclosed in the original specification and claims. Obviously, because the original specification and the claims did not fully disclose that the products in the present claims have clear medical functions and unexpected technical effects as required by the Patent Law, the modification results of the claims cannot be directly and undoubtedly derived from the specification and the original claims.

4. As the existing cGMP and PDE inhibitors can be used to treat ED, it has been suggested and suggested many times in the relevant literature, it is not difficult for ordinary technicians in this field to draw the results in the claims from these tips and suggestions.

On the above questions, Pfizer answered each "invalid reason" one by one, proving that there is no problem with the creativity of its patent. After that, the original Patent Reexamination Board of China National Intellectual Property Administration finally declared the patent authorized by the original research company Pfizer invalid through in-depth research. Pfizer was dissatisfied with the above decision of the original re-examination board, and immediately appealed to the Beijing No.1 Intermediate People’s Court to sue the original patent re-examination board, requesting the court to cancel its decision of invalidation. After repeated debates, in 2006, the Beijing No.1 Intermediate People’s Court officially announced the revocation of the decision of No.6228 made by the original Patent Reexamination Board. Since then, Pfizer’s Viagra has made huge profits in China every year, but sildenafil produced by domestic generic drug companies cannot be listed. This situation continued until the listing of domestic sildenafil "Jinge" in 2014.

The importance of "public opinion"

The application for "invalid patent" can not be disputed only after authorization. When the application documents appear, they can be questioned in the form of "public opinions". Article 48 of the Detailed Rules for the Implementation of the Patent Law stipulates that "from the date of publication of an application for a patent for invention to the date of announcement of the grant of a patent right, anyone may put forward opinions to the patent administration department of the State Council and explain the reasons", which is also called "public opinions" in the industry. Pharmaceutical enterprises should make full use of this provision to protect their own interests to the maximum extent.

The rosiglitazone case illustrates the importance of "public opinion". In 1993, GlaxoSmithKline applied for a series of patents including pharmaceutical compounds and compositions, such as the invention patent application with the application number of CN98805686.0, which requested to protect the pharmaceutical composition containing 2mg~8mg of rosiglitazone. The application date was June 2, 1998, the publication date was July 5, 2000, and it was authorized on July 2, 2003. It can be seen that it took about three years from the disclosure of the patent application to the announcement of authorization. During these three years, the relevant enterprises in China did not put forward any "public opinions".

In 2004, when Shanghai Sanwei Pharmaceutical, Zhejiang Wanma Pharmaceutical, Chongqing Taiji Group and other domestic enterprises have invested a lot in research and development of this drug or entered the stage of drug registration, they suddenly received a lawyer’s letter from GlaxoSmithKline, claiming that the products developed by the above-mentioned enterprises infringed their patent ZL98805686.0, demanding that the above-mentioned enterprises stop the research and development and listing of related products and compensate for the losses. As a result, these enterprises jointly requested the original patent reexamination board to declare the patent invalid. Although the case ended in GlaxoSmithKline’s abandonment of the patent, it lasted for a long time and had a great impact, causing huge losses to China enterprises.

Analyzing the case, when domestic pharmaceutical companies were ready for production and even obtained the approval of drug production, they found that they were facing the infringement lawsuit of foreign pharmaceutical companies, so they passively responded and rushed to the original Patent Reexamination Board to file a patent invalidation request in an attempt to invalidate the patent. In this case, even if the patent right can finally be declared null and void in whole or in part, China enterprises still face huge market risks and interest losses due to the long trial period and long-term uncertainty of rights.

In fact, an application for a patent for invention will be published within 18 months from the date of filing (unless the applicant requests it to be published in advance), and then the Patent Office will start substantive examination on it at the request of the applicant. If the examiner thinks that the patent application conforms to the relevant provisions of the Patent Law and the Detailed Rules for the Implementation of the Patent Law, the patent right will be granted and announced to the public, otherwise, it will be rejected. After the patent is granted, anyone (the third party) who thinks there is a problem with the patent grant may go to the relevant department to request that the patent be declared invalid. Of course, if you are not satisfied with the invalidation or review decision made by the relevant department, either party can also bring a lawsuit in court. Generally speaking, after an invention patent is published 18 months from the date of filing, it sometimes takes 2-4 years to decide whether to authorize it. At this stage, whether the patent application can be finally authorized is still in a pending state, which is the time allowed to put forward "public opinions" as stipulated in Article 48 of the Detailed Rules for the Implementation of the Patent Law. It can be seen that how to reduce the losses caused by patent disputes relatively, the "public opinion" before patent authorization is very important.

In recent years, Chinese pharmaceutical enterprises have paid more and more attention to the protection of intellectual property rights. The intellectual property departments of many large pharmaceutical companies have even reached the scale of 100 people. In addition, for some important patent applications, some pharmaceutical companies will take them to more professional patent agencies for secondary processing and polishing before submitting applications. It can be seen that pharmaceutical companies pay more and more attention to patent application and are more and more cautious about controlling patent quality. With the increasing number of patent challenges and invalid patent applications, the trend of domestic pharmaceutical companies turning from defending to attacking intellectual property rights has been initially established.

(Qiang Sen)

Front door ecological farm, back door sewage is discharged directly! Farmhouse becomes a blind spot of pollution supervision

An ecological farm built on the river bank, in the form of quadrangle dwellings, has green grass in the yard, and a sewage pipe is connected from the kitchen behind the yard to the river. Reporter Bai Tiantian photo

  Imagine a family driving to an ecological farm far away from the city on a weekend, experiencing country life and tasting delicious farmhouse food. How do you feel when we leave comfortably, but leave behind the black and smelly wastewater that is directly discharged into farmland and rivers?

  Nowadays, all kinds of farmhouses and ecological farms are blooming everywhere, becoming the hot spots of rural tourism. Half-monthly reporters have recently conducted field investigations in many places and found that many farmhouses have outstanding problems of "front door ecology and back door sewage discharge", and pollution prevention and supervision are lagging behind. Some farms that flaunt "ecology" are not worthy of the name, and the sewage discharge place has become a stinking ditch, and the lampblack discharge place has become a "black land".

  Ecological farms are not necessarily "ecological", and waste water and oil are discharged at will.

  Pastoral scenery, green ecology, native dishes … … This is a "propaganda language" played by many farmhouses and farms. Recently, a semi-monthly reporter walked into an ecological farm built on a river bank in a county in Dongting Lake area. The farm is a courtyard house with more than 10 boxes, green grass in the yard, cool breeze on the terrace near the river and pleasant environment. Walking through the yard to the back of the kitchen, you can see a 4-meter-long, covered with blue colored steel tiles, and some hidden pipes lead directly into the river. The water flowing out of the pipe is obviously dirty.

On a farm around a county town, kitchen sewage and waste were discharged into a small pond for a long time, filled with black or yellow wet and sticky dirt, next to a rice field and an irrigation canal. Reporter Bai Tiantian photo

  In this regard, the farm staff disapprovingly said: "The sewage in the kitchen is discharged like this, and it is washed away as soon as it rises."

  A farm close to a county town, the scene of sewage discharge is even more shocking. When the reporter asked the farm owner for half a month, how to discharge the sewage? The female boss’s answer is: "We discharged into the sewer." But when the reporter went to the back of the kitchen, a bad smell came head-on, and I saw a small pond next to it, full of black or yellow wet and sticky dirt. On one side of the pond, there are paddy fields and an irrigation canal — — It turns out that this is the so-called "sewer".

  In another mountainous town, the annual spring flower viewing season is the tourist peak season, and tourists come here in an endless stream. A farmhouse named "Central Local Restaurant" has a reception capacity of more than 20 tables. Half a month, the reporter saw that the oil pollution, dishwashing water and toilet sewage of this farmhouse lampblack machine all merged into the next canal. The farmhouse is surrounded by farmland, and the early rice is growing green. These blackened wastewater turns into irrigation water and flows into the fields.

  Similar pollution phenomenon is not a case. A person in charge of the environmental protection department said frankly that in the current rural environmental pollution, the wastewater, exhaust gas, lampblack and solid waste from farmhouses and farms are important sources of pollution. "Many farms are directly discharging pollutants in order to maximize their interests."

A farmhouse that focuses on "local dishes", the kitchen waste water is directly discharged into the canal behind the house, forming a black greasy dirt for many years. Reporter Bai Tiantian photo

  Shuguang Environmental Protection is a non-governmental environmental protection public welfare organization in Hunan. This year, they launched a survey on the water pollution in farmhouses. Tan Yongchao, director of water project, said that at present, his team members have visited more than 20 farmhouses on the spot and found that toilet sewage is generally treated by septic tanks, while most kitchen wastewater is "directly discharged".

  In April, Shuguang Environmental Protection conducted a sampling inspection of wastewater samples from the outlet of an ecological farm around Changsha. The test items included suspended solids, chemical oxygen demand, total phosphorus, total nitrogen and ammonia nitrogen. According to the test report, if compared with the pollutant discharge standards of urban sewage treatment plants, many indicators of the samples seriously exceed the standard. For example, the chemical oxygen demand (COD) is 373 mg/L, which is more than seven times that of Grade A standard and three times that of Grade III standard.

  "I pollute but I don’t control it", and environmental protection can only rely on "awareness"?

  During the tourist season or weekends and holidays, some farmhouses and ecological farms are bursting with popularity, and operators earn a lot of money. But when it comes to environmental protection, they often "have nothing to do with themselves and hang high", and the prevention and control of pollution can only rely on "awareness".

  In the interview, farmhouse operators generally showed two typical mentalities. One mentality is that "the law does not blame the public." An eco-farm owner pointed to the pipeline leading directly to the village canal and said without hesitation: "Sewage is directly discharged into the canal without treatment. In rural areas, everyone does this and it has no impact."

  One mentality is "I pollute and the government pays". After a half-month talk, reporters asked a number of operators and found that they generally lacked the concept of "who pollutes, who governs", and thought that pollution control is a matter for the government. The owner of the farm near the county said that it would cost thousands of dollars to remove waste water and waste oil once, which was not cost-effective, and should be paid by the government. Before the village dredged the canal, she didn’t clean the sewage pond of her farm by the way, and she still complained about it.

In a village famous for enjoying flowers in spring, the oil pollution, dishwashing water and toilet sewage of a farmhouse lampblack machine in rice fields are "three in one", and the blackened wastewater is directly discharged into the irrigation canal. Reporter Bai Tiantian photo

  On the other hand, some places lack restraint and supervision on the pollution of farmhouse music. A person in charge of the local environmental protection bureau said that in the past, rural environmental improvement focused on "visible garbage" and carried out cleaning projects for villages, schools and roads, but not enough attention was paid to the "root cause" of air, water and soil pollution. According to the regulations, environmental impact assessment should be carried out in the construction of ecological farms, but the local area is basically blank.

  In 2017, the Environmental Protection Bureau of Linyi County, Hunan Province investigated an ecological farm project and found that it was built without going through the EIA approval procedures, put into operation without supporting pollution control facilities, and made administrative penalties. However, similar cases are rare. Most of the farm operators interviewed by reporters in half a month said that they did not conduct environmental assessment, and the inspection of environmental sanitation rarely involved smoke exhaust, drainage and exhaust.

  Relatively speaking, star farms have done a good job in environmental protection. In a five-star farm with an area of more than 80 mu and an investment of tens of millions, facilities such as sewage purification tanks and fume purifiers are readily available, designed and installed by professional environmental protection companies. The owner of the farm said that the star rating has clear environmental protection requirements, so they conducted an environmental assessment and built pollution control facilities.

A five-star farm has done a good job in environmental protection, and built facilities such as sewage purification pond and lampblack purifier. Reporter Bai Tiantian photo

  Farmhouse "blooms more", and environmental protection should also "keep up step by step"

  With the rise of rural tourism and global tourism, farmhouses and ecological farms are showing the trend of "multi-point flowering". The reporter learned from the semi-monthly talk that in recent years, in key areas such as urban suburbs, reservoir wetlands and scenic spots, farmhouse music is gradually being brought into the scope of supervision and rectification, and environmental pollution problems have begun to spread to some remote counties and townships and emerging rural tourist spots.

  Liu Shuai, director of the Supervision Department of the Environmental Protection Committee of Hunan Provincial People’s Congress, said that at present, pollution prevention and control of farmhouse music is well done in developed areas such as the Yangtze River Delta and around big cities, but it is still weak in many other places, which should be further paid attention to and strengthened management.

  Liu Shuai believes that it is necessary to explore rural pollution control modes according to local conditions, such as building "upgraded versions" of constructed wetlands and septic tanks in villages with scattered populations. In the construction and operation of farmhouse music, the environmental impact assessment system should be implemented at the front end, and the departments of agriculture and tourism should be combined at the end to strengthen environmental law enforcement.

  Wang Gaoliang, deputy director of the Environmental Protection Bureau of Hengyang County, said that this year, the local environmental protection department will focus on rural environmental improvement, requiring farmhouses to standardize the installation of lampblack and sewage treatment facilities, and promote the construction of four sewage purification ponds and "constructed wetlands+oxidation ponds" suitable for rural areas. The basic requirement is that they cannot be discharged directly. If the farmhouse fails to meet the environmental protection requirements, a rectification letter will be issued and penalties will be imposed.

  Liu Hongli, Director-General of Shuguang Environmental Protection, suggested that the principle of "whoever pollutes should treat" should be adhered to for farmhouses and ecological farms. At the same time, the government can also introduce guiding measures, like remediation of aquaculture pollution, and give certain subsidies to the construction of pollution control facilities according to the scale of farmhouses, starting with newly-built farmhouses and star-rated farms, and then gradually solving the problem of stock pollution. (Talk to reporter Bai Tiantian for half a month)

Experts’ Interpretation: Working with the international community to control the environmental problems of new pollutants

  New pollutants endanger the ecological environment and human health, which is one of the global environmental problems. The CPC Central Committee and the State Council attached great importance to the treatment of new pollutants. Recently, the General Office of the State Council issued the Action Plan for the Treatment of New Pollutants (Guo Ban Fa [2022] No.15, referred to as the Action Plan), which pointed out the direction for the treatment of new pollutants in the future. The Action Plan embodies China’s idea of actively participating in global environmental governance, which is of great significance for building a beautiful China and building a community of life on earth.

  First, new pollutants are a common challenge facing the world.
  The environmental risk of new pollutants is an environmental problem faced by all countries in the world. The new pollutants mainly come from synthetic chemicals. DDT revealed by Silent Spring is one of the chemicals with typical new pollutant characteristics, and its harm spans half a century and involves every corner of the world. In order to protect the ecological environment and human health, developed countries such as Europe, America and Japan have been legislating to control the environmental risks of toxic and harmful chemicals since the 1970s. In 1992, Agenda 21 of Rio Conference on Environment and Development in Brazil defined the plan to reduce the global environmental risks related to chemicals, and then the world gradually took action and controlled some new pollutants with long-distance migration that may cause environmental and health hazards to the world. Among the 17 sustainable development goals for 2030 reached by the United Nations in 2015, Goals 3, 6 and 12 all involve the treatment of new pollutants, such as drastically reducing the number of deaths and illnesses caused by toxic and harmful chemicals and air, water and soil pollution by 2030.
  The treatment of some new pollutants needs global action. Besides being persistent, bioaccumulative, carcinogenic and teratogenic, some new pollutants also have the potential of long-distance migration, which can migrate across international boundaries with air, water or migratory species and be deposited in areas far away from their discharge points, causing worldwide environmental pollution problems. The treatment of such new pollutants requires global joint action. Therefore, the international community adopted the Stockholm Convention on Persistent Organic Pollutants in 2001. At present, there are 30 categories of persistent organic pollutants controlled by Stockholm Convention. Through global action, more than ten kinds of production and use have been eliminated all over the world.
  Second, controlling new pollutants will be a long-term task.
  New pollutants cover a wide range and are closely related to economic development and production and life. China is a big producer and exporter of chemicals. According to UNEP’s Global Chemicals Outlook, China’s chemical sales accounted for 37.2% of the world’s total in 2017, and it is expected to reach 50% of the world’s total in 2030. China is the main producer of chemicals newly listed in Stockholm Convention and under evaluation, such as short-chain chlorinated paraffin, decabromodiphenyl ether, DechloranePlus, chlorpyrifos and ultraviolet absorber (UV-328). These chemicals are consumed and used in many industries, and some chemicals are closely related to necessities such as agricultural production, daily necessities, semiconductors, aerospace products, etc. For example, the annual production scale of short-chain chlorinated paraffins can reach millions of tons, and chlorpyrifos is related to agricultural production and food security. However, it is difficult to develop their substitutes, and there may be conflicts in availability, performance, cost, environment and safety, so it is difficult to achieve perfection, which brings great challenges to the control of new pollutants in the future.
  One of the greater challenges to control new pollutants is to identify, evaluate and control the chemicals being produced and used. Both the Toxic Substances Control Act of the United States and the Regulation of Registration, Evaluation, Licensing and Restriction of Chemicals of the European Union have been faced with huge data and research and evaluation needs since their implementation, and have not fully achieved the control objectives of the original design regulations on new pollutants. At the level of international conventions, the Stockholm Convention only added 18 categories of persistent organic pollutants in 17 years. China is one of the countries with the richest types of chemicals. The existing chemical list includes more than 40,000 kinds, and nearly 100 new chemicals are listed every year. Limited research information shows that according to the screening criteria of Stockholm Convention, there are more than 100 chemicals in the above list that meet the screening criteria of persistence and bioaccumulation at the same time, and these hundreds of chemicals are potential new pollutants that need to be controlled. Although the contribution of China’s research results has been increasing in the process of adding new controlled substances to the Stockholm Convention, China still needs to carry out a large number of data surveys, environmental monitoring, environmental risk assessment and control in the future, and increase the pace of controlling the environmental risks of new pollutants.
  To sum up, new pollutants involve substitution and emission reduction, large industrial scale and long industrial chain, and are closely related to industrial and agricultural production and life. Protecting the ecological environment and human health and balancing the needs of economic development is an important basis for formulating and implementing new pollutant control programs. The identification and assessment of new pollutants that potentially need to be controlled depends on data investigation, a large number of scientific research results, environmental risk assessment and socio-economic impact assessment of control. The task of controlling new pollutants requires all-round coordinated promotion, which is extremely arduous.
  Third, work with the international community to prevent environmental risks of new pollutants.
  As early as 2001, China and the international community jointly promoted the formulation of the Stockholm Convention, and started cooperation with the international community to jointly control new pollutants. In the past twenty years, China has eliminated the production, use and discharge of a large number of new pollutants, protecting the global ecological environment and human health. During the same period, the national economy grew rapidly, and the share of chemicals produced increased from about 5% in the world to 37.2% in 2017, making it one of the countries with the largest chemical production and the most varieties, and people’s lives have been improved. At the same time, China is also facing new challenges and pressures. With the progress of scientific cognition and the demand for higher quality of life, some chemicals that we used to think were harmless are gradually considered unsuitable for further production and use. By implementing the Action Plan, China will work with the international community to prevent the environmental risks of new pollutants.
  First, learn from the existing international convention mechanism and implement the control of new pollutants in accordance with international law. While perfecting China’s laws and regulations, establishing and perfecting the new pollutant control system, we should use the mechanism of international conventions to identify, evaluate and control the environmental risks of chemicals together with the international community, which will not only realize the control of new pollutants in China, but also promote the action of new pollutant control on a global scale, promote the green development of the global chemical industry and realize global environmental governance.
  The second is to increase the scientific and technological investment of the state and enterprises in the treatment of new pollutants, scientific decision-making, and precise control. Fully understanding the decision-making information such as scientific research is the foundation of controlling new pollutants, continuously increasing the scientific and technological investment of the state and enterprises in controlling new pollutants, mastering the source, fate, harm and control technology of potential new pollutants, making scientific decisions, and realizing accurate and effective control.
  The third is to make use of international scientific research and management experience, evaluate and screen out key new pollutants as soon as possible, and establish a mechanism to implement control. Actively carry out international cooperation, and make full use of global forces, especially scientific research and management experience, to promote and accelerate the screening of new pollutants and environmental risk management and control in China, in view of some potential new pollutants that may not meet the global migration attributes, in the case of insufficient research information in China. At the same time, learn from the financial mechanism of international conventions, and establish international, national, local and enterprise financial mechanisms to control new pollutants.
  Fourth, we will continue to help other developing countries strengthen their ability to control new pollutants, spread China’s knowledge and China’s experience, and prevent the transfer of new pollutants. As a developing country, China’s experience in the discovery, research and management of new pollutants may be suitable for other developing countries. China can continue to provide technical training and capacity building for developing countries, help other developing countries to prevent the transfer of new pollutants as products or wastes, and contribute China’s strength to building a life community on Earth.
  The new pollution control action reflects the historical responsibility of the CPC Central Committee to participate in, contribute to and lead global environmental governance, and will continue to contribute China’s plan, China’s wisdom and China’s strength to global environmental governance. The new pollution control action is also the need to build a beautiful China and maintain sustainable green chemistry and economic growth in China. Building a new pollution control system in China and protecting the earth’s homeland will help to realize the global pursuit of high-quality life, achieve the goal of sustainable development in 2030, realize the harmonious coexistence between man and nature, and build a community of life on earth.
  Author: Hu Jianxin (Professor, Peking University Institute of Environmental Science and Engineering)

Does the Foreign Sanctions Law have an impact on foreign investment? Ministry of Foreign Affairs responded

  On June 11th, Foreign Ministry Spokesperson Wang Wenbin held a regular press conference. A reporter asked whether the spokesman was worried about the negative impact on foreign investment after the passage of the Foreign Sanctions Law.

  Wang Wenbin said that the Legal Affairs Committee of the National People’s Congress Standing Committee (NPCSC), China has introduced the relevant situation. Around the two sessions this year, some NPC deputies, Chinese People’s Political Consultative Conference members and people from all walks of life put forward opinions and suggestions that it is necessary for the state to formulate a special anti-foreign sanctions law to provide strong legal support and guarantee for China to counter foreign discriminatory measures according to law. According to the relevant work arrangement, the the National People’s Congress Standing Committee (NPCSC) Law Committee carefully studied the legislative suggestions put forward by various parties, summarized the counter-measures practice and related work practices in China, sorted out the relevant situation at home and abroad, solicited the opinions of relevant departments and experts of the central and state, and drafted and formed the draft of the anti-foreign sanctions law. According to the legislative procedure, China the National People’s Congress Standing Committee (NPCSC) deliberated the draft twice in April and June, respectively. The Law Working Committee solicited the opinions of the central and relevant state organs on the draft, and the Constitution and Law Committee of the National People’s Congress revised and improved the draft according to the deliberation opinions of the Standing Committee and opinions from all sides. At present, the Anti-Foreign Sanctions Law has fully absorbed opinions from all sides, reflected the common wishes of the people of China, and conformed to the basic norms of international law and international relations.

  Wang Wenbin pointed out that regarding the influence of the Anti-Foreign Sanctions Law on foreign investment, I don’t see an inevitable connection between the two. If there is, it is the enactment of the Foreign Sanctions Law, which provides a predictable legal environment and a stable and predictable business environment for enterprises from all countries to develop in China. At the 29th meeting of the 13th the National People’s Congress Standing Committee (NPCSC), the Hainan Free Trade Port Law and the Decision on Authorizing the Shanghai Municipal People’s Congress and its Standing Committee to Formulate Laws and Regulations of Pudong New Area were also passed, which are new measures for China to deepen reform and open wider to the outside world.

  Wang Wenbin emphasized that China has always welcomed and supported foreign enterprises to conduct business and cooperation in China and protect their rights and interests according to law. China will only open wider to the outside world, and we will continue to strive to create a better business environment for foreign enterprises and share China’s development opportunities with the world. (CCTV reporter Huang Huixin Kong Luyuan)

China CDC: Dinner is not recommended, and it is not recommended to bring infants to eat in the hall.

  Cctv newsOn April 23rd, the State Council Joint Prevention and Control Mechanism held a press conference to introduce the popularization of scientific knowledge of prevention and control in COVID-19 and answer questions from the media.

  The reporter asked whether it is still possible to eat in restaurants, and if so, how to protect them.

  Feng Luzhao, a researcher at China CDC, said that at present, large-scale dinners are still not recommended, and it is not recommended to bring infants who have no self-care ability to eat in class. It is recommended to choose some restaurants with good sanitary conditions for ordinary dining, make an appointment before eating, and eat at the wrong peak to avoid crowding.

  Before entering the restaurant, you should cooperate with the staff to take temperature measurement and register. If you have fever, you should not enter the restaurant. During your stay in the restaurant, you should minimize contact with those public facilities, do a good job of hand hygiene, and wash your hands before meals and after going to the toilet. In the process of eating, try to keep interpersonal distance with others and pay attention to cough etiquette. When many people eat together, it is recommended to use public chopsticks and spoons to reduce the chance of contact and transmission and reduce the risk of infection.

Beijing’s key monitoring businesses recorded 9.27 billion yuan in two holidays, and more than 500 activities stimulated consumption vitality.

  BEIJING, Beijing, October 6 (Reporter Lu Shaowei) During the Mid-Autumn National Day holiday in 2023, the department stores, supermarkets, specialty stores, restaurants and e-commerce enterprises monitored by the Beijing Municipal Bureau of Commerce achieved sales of 9.27 billion yuan, a year-on-year increase of 21.8%. The passenger flow of 60 key business districts in Beijing reached 45.092 million. The "Beijing Consumption Season" series of activities linked consumption resources in various fields, such as cultural tourism, sports and rural areas, and held more than 500 consumption promotion activities together with market operators, effectively stimulating the vitality of holiday consumption.

  On the 6th, the Beijing Municipal Bureau of Commerce said that the consumer market in Beijing was prosperous and active during the two holidays. Commercial departments at all levels co-ordinate production safety and daily necessities, carefully organize market supply and service guarantee, and the supply of grain, oil, vegetables, pork, etc. is sufficient and the price is stable.

  Various districts launched special theme activities.

  The three major activities of Beijing Consumption Season combine the diverse scenes of business travel style to create a rich holiday atmosphere. The special activities of Xicheng District’s "Welcome to Golden Autumn Tesco Festival", Haidian District’s "Community Consumption Festival", Fengtai District’s "Shopping Carnival" and Yanqing District’s agricultural special coupons were launched simultaneously, Dongcheng District’s "East of the Forbidden City" issued tens of millions of travel subsidies, and Pinggu District’s "Buy Good Gifts and Enjoy Pinggu" sent out 1.5 million yuan of general coupons.

  The consumption scene is renewed and upgraded.

  The first store is popular for the first time, and new landmarks are consumed to lead the fashion. Five shopping malls, namely CITY PARK in Lin ‘ao, Wanda in Wukesong, wanda plaza in Dongba, LOMO in Kunxihui, and Tangu Slow Flash Plaza, opened simultaneously to attract customers and drain, with an additional commercial area of over 600,000 square meters. More than 130 brands of Longhu Beijing Beiyuan Tianjie improved the consumption experience, the first store of British suitcase brand Globe-Trotter appeared in mainland China, and the first store of street fashion brand BONELESS in Beijing settled in THE BOX to enrich the holiday consumption supply. Chaoyang Joy City’s "Traveling Around the World Art History", INDIGO’s "Elephants from the Heart Wandering with Flowers", Blue Harbor’s "Cats and Miaomiao Interactive Space", Oriental Xintiandi’s "30th Anniversary of Jurassic Park" and Beijing’s "Phantom of the Theater" are the first exhibitions that combine art, trends and interesting elements to start an immersive experience and stimulate new vitality of holiday consumption.

  The "national tide" and "national wind" are heroic, and the charm of new consumption scenes is highlighted. The "MADE BY Beijing" market on the banks of Liangma River gathers more than 30 time-honored and trendy products to become holiday punching places in online celebrity. Fengke Wanda National Tide Cultural Show, Kaide MALL Sun Palace Poetry Gallery, Chaoyang Heshenghui Mingyue Huazhang Garden and Huaxi LIVE Lantern Parade bring immersive national tide experience. Time-honored shops in Qianmen Street joined forces with the "punch card seal" to stop, and Beijing Square "Free FUN Market" and Longfu Temple "Sanxingdui Immersed Light and Shadow Exhibition" created a consumption scene of "fireworks+new national tide". Sanlitun Taikooli’s "Rhythmic Fantasy Art Exhibition", Xidan Renewal Field’s "Miracle Coffee Flash Exhibition", Longhu Changying Tianjie’s "Urban Fashion Season" and COFCO Xiangyun Town’s "Outdoor Art Season" create a rich holiday atmosphere.

  The heat of automobile consumption is rising

  Multi-preferential car purchase boom, Haidian District "Car Theme Life Festival", Chaoyang District "Chaochaoyang" car purchase, Mentougou District "New Car Happy Purchase and Huiju Mentougou" exhibition and sales collection meet diverse car purchase needs, Fengtai District and Changping District launched disaster-stricken special car consumption subsidies, Tongzhou District, Daxing District, Pinggu District, Economic Development Zone and other seven districts issued a total of over 30 million car coupons, and the leverage effect continued to release to help car consumption heat up. During the holiday period, the sales of monitored automobile sales enterprises increased by 69.9% year-on-year.

  Green consumption becomes a fashion.

  During the "2023 Beijing Consumer Season Home Rejuvenation Festival", four sections of "Smart Home", "Green Living", "Comfortable Living" and "Huili Warm Living" were built. The applicable products of "Jingcai Green" coupons were increased to 62 categories, and the distribution platforms were expanded to 24. Many financial institutions simultaneously carried out activities and superimposed concessions, and high-quality experiences promoted the release of home consumption potential. Haidian District "Brand Consumption Festival", Fengtai District "Warm Heart Community Tour" and Changping District "Home Appliances Rejuvenation Season" linked more than 100 brand services to upgrade. IKEA’s "Huanxin Shopping Festival" promotes the storage of good things. Suning Yijia Madian Store focuses on family scene solutions and creates a new hot spot for home decoration consumption. Since its opening on September 28th, its sales have exceeded 35 million.

  Tourism heats up, and foreign consumption peaks.

  During the two holidays, city tours, Beijing outings and micro-vacations have significantly warmed up, and foreign consumption has reached its peak. 30 theme routes of "Walking in Beijing" and 6 micro-holiday destinations deeply experience the connotation of the city, 41 leisure agricultural routes in autumn promote beautiful countryside, and the series of activities of "China Farmers Harvest Festival" in Beijing promote the harvest and beauty.

  Around the theme of folk culture, flower exhibition, popular science experience and festival performances, more than 100 special cultural activities have been held in Beijing’s parks to create a festive atmosphere. Changping District’s "Traveling in the suburbs of Beijing", Pinggu District’s "Enjoying Farming" and Mentougou District’s "Jazz Festival of Good Things" have created a new scene of integrated consumption. Universal Studios and POP MART City Paradise enjoy exclusive discounts, and the Grand Canal Music Festival, Happy Valley "Guochao Street Art Festival", Liangmahe "International Waterfront Night Tour", Yanqi Lake "China Theme Festival Exhibition" and World Garden Park "Lantern Art Festival" enrich holiday experience.

  During the two festivals, Beijing held 43 sports competitions and group activities, such as football and tennis. The 27th round of the 2023 Super League attracted 41,000 spectators, and the ticket sales of the 2023 China Tennis Open reached 33 million yuan. The top flower-sliding show of Ice Dreams and Rain made its debut in the "Ice Ribbon", leading the new trend of sports consumption. According to the business data of UnionPay, the consumption of accommodation and travel ticket sales increased by 30.1% and 20.2% respectively year-on-year, among which the consumption of accommodation and travel ticket sales by foreign tourists increased by 35.2% and 46% respectively.

  3630 cultural and artistic activities enrich holiday life

  During the two festivals, Beijing launched 3,630 cultural and artistic activities to enrich holiday life. Quyi, drama, musicals and concerts showed the style of the new era of the capital in various forms. China Opera Culture Week, beijing music festival and "Double Olympics City" stage art performance season show the charm of cultural consumption, and a series of activities such as Xinhua Bookstore, Book Building and People’s Literature Publishing House add color to holiday life. More than ten multi-theme films, such as Rock-solid, Volunteer Army: Attack by Heroes, and Moscow Action, competed for the National Day file. barley net, Cat’s Eye, Alipay and WeChat offered discounts to lift the whole city’s viewing craze. According to Dengta Data, as of 12: 00 on the 6th, Beijing’s box office revenue exceeded 100 million yuan. According to the business data of UnionPay, the consumption of culture and entertainment increased by 18% year-on-year. (End)

Anaya, which was hard to get a ticket, was once an unfinished building that no one cared about.

Speaking of Anaya, you probably didn’t know what it was a few years ago.But in the last two years, it can be said that the fire is outrageous.The circle of friends and various social networks in Weibo are full of people punching in to play.

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Because it’s only 3 hours’ drive from the Imperial Capital, it’s also a middle-class family in Beijing, and it’s the best vacation place to escape from the noise and the city.The most humanistic seaside community in legend.

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House prices here are soaring, and they can’t be sold at all.Several developers abandoned them and left.Up to now, house prices have soared to more than 30,000/flat.It costs 3,000 yuan to stay in a homestay in the peak season, and the annual sales are about 3 billion.

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01

Why is Anaya on fire?

In 15 years, a video "The Loneliest Library in China" completely caught Anaya on fire.Set a hit rate of 600 million,Overcrowding Anaya overnight,At most, there are more than 2,000 visitors a day, and the most lonely library has become the most lively library.

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Although it is only over 450 square meters, it has a sense of design.And you can see it when you look upThe endless sea,Completely in line with the preferences of contemporary young people.

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GO is in the place of nowhere.

On the entire coastline

Just this one building

When the sea breeze blows, it is full of desolation.

It does look lonely enough.

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But you know what?

Before the lonely library became a phenomenal explosion

Anaya is a place that everyone dislikes.

There are no shopping malls, hospitals or even locals nearby.

Whether it is from Beidaihe Railway Station

Or Qinhuangdao city is very far away.

There is only an endless "gold coast"

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Anaya property at that time

Besides being a sea view room,

Actually, there is no outstanding advantage at all.

Naturally, it can’t be sold and nobody cares.

Developers have changed wave after wave.

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Until the emergence of Ma Yin, the "taker"

He completely revitalized Anaya.

Take a fancy to wenlv real estate in the past

Rich and idle people are different after 60 and 70.

He focused on the new middle class aged 25-35.

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In fact, the word Anaya

It was Ma Yin who put it forward.

Anaya is a transliteration of aranya in Sanskrit.

It means "the quiet place on earth, the place to find the id"

As for why it’s called this

It is because it is literary and tonal!

The name alone distinguishes it from ordinary real estate.

Naturally, it is also the new middle-class literary youth who are attracted.

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Whether it’s geographical location or seaside scenery.

Anaya is not even the best.

Compared with ordinary real estate

Ma Yin is actually selling.

The values of the ideal life of the new middle class

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Ma Yin passed a series of reforms

Completely put Anaya

Become a community of spiritual space

There are not only markets, bars and golf courses here.

Gallery, bookstore, sports center …

Anaya racecourse

Anaya children’s activity center

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Anaya canteen

While meeting the needs of residents’ lives

A series of artistic landmarks have also been established.

Free for tourists.

Take Anaya from ordinary real estate

It has become a place for online celebrity to punch in.

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Anaya auditorium

02

What did you do after the fire?

Ma Yin’s appearance

It can be said that the real estate of Anaya

Play a king’s bomb from a bad hand

In these five years of operation,

From selling houses to selling services.

From selling services to selling lifestyles.

From selling lifestyle to selling values.

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Anaya life element supermarket

Anaya is no longer today.

A traditional real estate project

But became aBrand of great lifestyle

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Anaya Sports Center

From the invitation of Ma Yin in 2014

Dong Gong, Architect of Straight Building

On Anaya beach

Designed two artistic landmarks to begin with.

(Lonely Library and Anaya Auditorium)

After that, all the landmarks here

Almost all of them are written by masters in the architectural field.

Have a very high tonality

And full of artistic and design feelings.

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Anaya auditorium

Straight building

Anaya auditorium distance

Lonely library is only 300 meters.

Staring at each other with the library.

Both are the spiritual heights of Anaya.

Let people calm down at the seaside.

Feel nature, feel yourself.

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From a distance

Anaya Auditorium is like a boat.

Suspended on this beach

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Although it’s called the auditorium

But there is no priest here.

You can’t have a wedding

I want to punch in the auditorium and take photos.

Remember to make an appointment in advance.

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Dune art museum

OPEN construction office

In 2018, it is still on the Gold Coast.

A building was born

Dune Art Museum, the only one in China.

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This art gallery is from OPEN architecture office.

The design was inspired by digging sand in caves and children’s beaches.

Much like the most primitive living form of human beings

Perfect and natural integration.

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It took more than two years to finalize the design scheme.

Because the facade of the whole building is curved

The later construction is even more difficult.

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Overlooking the completed Dune Art Museum.

Covered with vegetation and sand.

There is no roof, only skylights, holes and sea viewing platforms.

Give people a feeling of being between the sea and the sky.

It’s so romantic.

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Anaya art center

Ruen design

In addition, Sean and Hu Rushan designed by Ruen.

Also received an invitation from Anaya.

Among the many residential buildings in Beidaihe town, Anaya

Designed an art center.

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The facade of the building consists of

Cut concrete bricks are spliced together.

Windows are inserted in it.

The most shocking thing is that

In the center of the building

Dig a frustum of a cone space

Form an annular stepped theater

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While satisfying the art exhibition

Can be used as a public activity space for community residents.

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In addition to exhibiting designs, the Anaya Art Center

Architecture itself is like a work of art.

The same existence

At the same time, this building also won this year’s

DFA Asia’s Most Influential Design Award!

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Exhibition, performance and installation art of Anaya Art Center

Anayayun exhibition center

mad architects

Look at this streamlined design

Did you also guess?

This building comes from China.

Famous architect Ma Yansong

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Perfect white tone

Hyperbolic glazed glass facade

As if it were really a white cloud.

Fall from the sky to the grass slope

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It’s like walking into the sky

However, Anayayun only started construction in August 2019.

Those who want to punch in will have to wait until next year.

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Paopao children restaurant

Wutopia Lab office

This children’s restaurant used to be a clubhouse.

Architects and couples file Yu Ting and Min Erni.

It has been rebuilt.

On the basis of the original facade

Re-covered with a layer

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Outdoor yellow spiral staircase

Can directly enter the "forest of light" space on the second floor.

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The interior of the restaurant is mainly white.

Paired with bright yellow.

It’s simply beautiful.

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Go downstairs after dinner.

Is the children’s play space.

It seems to be placed in an immersive starry sky pavilion.

Countless bubble balls not only make children enjoy it

Even adults should be moved!

Anaya coffee house

Odd design office

This coffee shop is located in Anaya Park.

Smooth surface design is like a big hat.

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The whole coffee shop has no walls.

But all the glass facades are used.

Let you sit in it and you can

Enjoy the beauty brought by nature and sunshine.

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Coffee shop under the night

Under the care of lights and water.

Like a boat floating in the air.

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It’s hard to imagine that even a small cafe

Are designed so tastefully.

What is impossible in Anaya?

Look at Anaya now.

It reminds me of Seto Inland Sea in Japan.

Because artists such as Tadao Ando

A series of designs on the island

Let an island polluted by garbage

It has become a tourist attraction full of artistic flavor now.

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In fact, Anaya is the same

From the original unattended Wenlv real estate

Now it has become a holy place for punching cards in online celebrity.

Although there are still many netizens who don’t recognize it

I think Anaya is made by marketing.

There are a lot of people in the peak season, the house price is very expensive, and there is nothing interesting.

But you should know that Anaya is not really a scenic spot.

It is the tourism real estate project in itself.

The main business is "selling houses" and the sideline business is sightseeing.

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There is no denying that Anaya’s development model

It is definitely a clear stream in the real estate industry.

Using architecture and art to promote local development

Not only makes the whole community become advanced and tasteful

It also proves that Chinese.

It’s not without good aesthetics and good design!

Anaya now

It’s like a paradise for urbanites

Full of artistic spiritual space

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(The article comes from Puxiang Industrial Design Station. If there is any infringement, please contact to delete it.)

ACE2 receptor protein "nanobubbles" can prevent and treat COVID-19.

  Science and Technology Daily, Beijing, January 23rd (Intern reporter Zhang Jiaxin) According to a paper published in the journal Nature Communication on the 20th, scientists from Northwestern University School of Medicine and the University of Texas, The University of Texas MD Anderson Cancer Center, found in preclinical research that there are natural nano-sized bubbles containing angiotensin converting enzyme 2 protein in the blood of COVID-19 patients, and found that it can prevent a wide range of Covid-19 strains from being infected, including many current Covid-19 variants and possible coronaviruses in the future. Once developed into a therapeutic product, it can be used as the least toxic biotherapy method to benefit mankind.

  EvACE2 protein is a tiny lipid (fat) vesicle with the size of nanoparticles, which expresses ACE2 protein (the receptor of Covid-19). Scientists say that these bubbles can be used as bait in the body to "lure" Covid-19 away from the ACE2 protein on the cell.

  Covid-19 spike protein "grabs" the "handle" of evACE2, but not the intracellular ACE2, which can prevent the virus from entering human cells. Once caught, the virus will either float around harmlessly, or it will be cleared by macrophage immune cells, and it will never cause infection again.

  Dr Lagu Karuri, co-senior author of the study and chairman of The University of Texas MD Anderson Cancer Center Cancer Biology, said that the key of this study is to identify the naturally occurring extracellular vesicles in the body, and these vesicles express ACE2 receptors on their surfaces, which is part of the normal adaptive defense against Covid-19. On this basis, they found a new potential therapy to use this natural defense against Covid-19.

  This study shows for the first time that evACE2 protein can block the original strain with the same or better effect against the new Covid-19 variety. The researchers found that these evACE2 nanobubbles exist in human blood, which is a natural antiviral reaction. The more serious the disease is, the higher the level of evACE2 detected in the patient’s blood.

  "Whenever new Covid-19 variants proliferate, the initial vaccines and therapeutic antibodies may lose resistance to Alpha, Beta, Delta and the latest Omicron variants." Dr. Liu Huiping, associate professor of pharmacology and medicine at feinberg Medical College of Northwest University, said, "However, the beauty of evACE2 lies in its super ability to prevent a wide range of coronavirus strains, including the current Omicron, and even the future coronavirus from infecting humans."

  Studies on mice show that when Covid-19 spreads to the airway through droplets, evACE2 has therapeutic potential to prevent or block infection.

  One of the biggest challenges in fighting the COVID-19 epidemic is the moving target of the virus, which constantly evolves into a new virus strain (variant) with mutation. There are various changes in the spike protein of these new virus strains, which may lead to an increase in infection rate and breakthrough infection.

  At present, the team is applying for a patent on evACE2, with the goal of cooperating with industry partners to develop evACE2 as a biotherapy product (nasal spray or injection therapy) to prevent and treat COVID-19.